Revised parameter estimates for water data sets after fixing the transit time
| Identifier . | Normalization factor, bw . | Transit time, Δ, d* . | Loss rate from blood, z, d−1 . | Proliferation rate, p, d−1 . | Blood half-life, d . |
|---|---|---|---|---|---|
| Heavy water | |||||
| A | 4.30 ± 0.03 | 5.7* | 0.93 ± 0.00 | 0.242 | 0.75 |
| B | 4.72 ± 0.02 | 5.7* | 0.96 ± 0.01 | 0.250 | 0.72 |
| C | 4.88 ± 0.07 | 5.7* | 0.84 ± 0.00 | 0.218 | 0.82 |
| D | 3.59 ± 0.12 | 5.7* | 0.84 ± 0.00 | 0.218 | 0.82 |
| E | 3.89 ± 0.04 | 5.7* | 1.34 ± 0.16 | 0.348 | 0.52 |
| DW04 | 4.40 ± 0.15 | 5.7* | 1.13 ± 0.24 | 0.294 | 0.62 |
| DW09 | 3.65 ± 0.20 | 5.7* | 0.68 ± 0.00 | 0.177 | 1.01 |
| DW10 | 4.37 ± 0.25 | 5.7* | 0.80 ± 0.19 | 0.208 | 0.87 |
| DW11 | 3.14 ± 0.14 | 5.7* | 0.92 ± 0.19 | 0.239 | 0.75 |
| Mean ± SD | 4.10 ± 0.57 | 0.94 ± 0.19 | 0.244 ± 0.051 | 0.77 ± 0.14 | |
| Median | 4.30 | 0.92 | 0.239 | 0.75 |
| Identifier . | Normalization factor, bw . | Transit time, Δ, d* . | Loss rate from blood, z, d−1 . | Proliferation rate, p, d−1 . | Blood half-life, d . |
|---|---|---|---|---|---|
| Heavy water | |||||
| A | 4.30 ± 0.03 | 5.7* | 0.93 ± 0.00 | 0.242 | 0.75 |
| B | 4.72 ± 0.02 | 5.7* | 0.96 ± 0.01 | 0.250 | 0.72 |
| C | 4.88 ± 0.07 | 5.7* | 0.84 ± 0.00 | 0.218 | 0.82 |
| D | 3.59 ± 0.12 | 5.7* | 0.84 ± 0.00 | 0.218 | 0.82 |
| E | 3.89 ± 0.04 | 5.7* | 1.34 ± 0.16 | 0.348 | 0.52 |
| DW04 | 4.40 ± 0.15 | 5.7* | 1.13 ± 0.24 | 0.294 | 0.62 |
| DW09 | 3.65 ± 0.20 | 5.7* | 0.68 ± 0.00 | 0.177 | 1.01 |
| DW10 | 4.37 ± 0.25 | 5.7* | 0.80 ± 0.19 | 0.208 | 0.87 |
| DW11 | 3.14 ± 0.14 | 5.7* | 0.92 ± 0.19 | 0.239 | 0.75 |
| Mean ± SD | 4.10 ± 0.57 | 0.94 ± 0.19 | 0.244 ± 0.051 | 0.77 ± 0.14 | |
| Median | 4.30 | 0.92 | 0.239 | 0.75 |
Parameters are as explained in Table 2.
Values denote the fixed value of transit time, Δ, in this model.