Table 2

Top validated SNPs (meta-analysis P < 1 × 10−5) are enriched in enhancers active in MSCs

Tissue typeAll enhancersStrongest enhancers*
Fold enrichmentPFold enrichmentP
Bone marrow–derived MSC cultured cells .0148 4.3 2.81 × 10−4 
Adipose-derived MSC cultured cells 1.8 .011 1.9 .068 
Tissue typeAll enhancersStrongest enhancers*
Fold enrichmentPFold enrichmentP
Bone marrow–derived MSC cultured cells .0148 4.3 2.81 × 10−4 
Adipose-derived MSC cultured cells 1.8 .011 1.9 .068 
*

Strongest enhancer chromatin state as previously defined.26 

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