Top validated SNPs (meta-analysis P < 1 × 10−5) are enriched in enhancers active in MSCs
Tissue type . | All enhancers . | Strongest enhancers* . | ||
---|---|---|---|---|
Fold enrichment . | P . | Fold enrichment . | P . | |
Bone marrow–derived MSC cultured cells | 2 | .0148 | 4.3 | 2.81 × 10−4 |
Adipose-derived MSC cultured cells | 1.8 | .011 | 1.9 | .068 |
Tissue type . | All enhancers . | Strongest enhancers* . | ||
---|---|---|---|---|
Fold enrichment . | P . | Fold enrichment . | P . | |
Bone marrow–derived MSC cultured cells | 2 | .0148 | 4.3 | 2.81 × 10−4 |
Adipose-derived MSC cultured cells | 1.8 | .011 | 1.9 | .068 |
Strongest enhancer chromatin state as previously defined.26