Table 1 Doses of hepatitis vaccines for... | American Society of Hematology

Table 1

Doses of hepatitis vaccines for immune-competent recipients by age

Vaccine	Dose of antigen(s)	Schedule (0 mo = initiation of vaccination)
Vaccine	Dose of antigen(s)	Dose 1	Dose 2	Dose 3
HAV (Havrix, GlaxoSmithKline)
0-18 y	760 U (0.5 mL)	0 mo*	6 mo*	NA
>18 y	1440 U (1 mL)	0 mo*	6 mo*	NA
HBV (Engerix, GlaxoSmithKline)
<19† y	10 mcg (0.5 mL)	0 mo*	2 mo	6 mo*
≥20 y	20 mcg (1 mL)	0 mo*	2 mo	6 mo*
*HAV/HBV (Twinrix, GlaxoSmithKline)**
≥18 y	760 U HAV + 20 mcg HBV (1 mL)	0 mo	2 mo	6 mo

Vaccine	Dose of antigen(s)	Schedule (0 mo = initiation of vaccination)
Vaccine	Dose of antigen(s)	Dose 1	Dose 2	Dose 3
HAV (Havrix, GlaxoSmithKline)
0-18 y	760 U (0.5 mL)	0 mo*	6 mo*	NA
>18 y	1440 U (1 mL)	0 mo*	6 mo*	NA
HBV (Engerix, GlaxoSmithKline)
<19† y	10 mcg (0.5 mL)	0 mo*	2 mo	6 mo*
≥20 y	20 mcg (1 mL)	0 mo*	2 mo	6 mo*
*HAV/HBV (Twinrix, GlaxoSmithKline)**
≥18 y	760 U HAV + 20 mcg HBV (1 mL)	0 mo	2 mo	6 mo

NA, not applicable; U, enzyme-linked immunosorbent assay units of HAV.

Immune-competent adults can alternatively be vaccinated for HAV and HBV with just 3 doses of Twinrix at 0, 2, and 6 mo.

Pediarix (GlaxoSmithKline) can be substituted for age >6 wk and ≤7 y, and it also contains DTaP and IPV.