Adverse events during treatment
| Adverse events, n (%) . | HD-DXM . | PDN . | ||
|---|---|---|---|---|
| Total (n = 95) . | ≥60 y (n = 18) . | Total (n = 97) . | ≥60 y (n = 20) . | |
| ALT | 1 (1.1) | 0 (0) | 0 (0) | 0 (0) |
| Arthralgia | 0 (0) | 0 (0) | 2 (2.1) | 1 (5.0) |
| Cushingoid appearance | 0 (0) | 0 (0) | 13 (13.4) | 2 (10.0) |
| Diarrhea | 0 (0) | 0 (0) | 1 (1.0) | 0 (0) |
| Dizziness | 2 (2.1) | 1 (5.6) | 5 (5.2) | 2 (10.0) |
| Edema | 0 (0) | 0 (0) | 4 (4.1) | 2 (10.0) |
| Fatigue | 1 (1.1) | 0 (0) | 4 (4.1) | 1 (5.0) |
| Fever | 1 (1.1) | 0 (0) | 0 (0) | 0 (0) |
| Hyperglycemia | 4 (4.2) | 1 (5.6) | 6 (6.2) | 3 (15.0) |
| Hypertension | 4 (4.2) | 2 (11.1) | 8 (8.2) | 3 (15.0) |
| Infection | 0 (0) | 0 (0) | 3 (3.1) | 1 (5.0) |
| Insomnia | 8 (8.4) | 3 (16.7) | 5 (5.2) | 2 (10.0) |
| Mood disorders | 7 (7.4) | 2 (11.1) | 4 (4.1) | 1 (5.0) |
| Nausea | 2 (2.1) | 1 (5.6) | 3 (3.1) | 1 (5.0) |
| Palpitation | 2 (2.1) | 1 (5.6) | 1 (1.0) | 0 (0) |
| Peptic ulcer | 2 (2.1) | 0 (0) | 5 (5.2) | 1 (5.0) |
| Weight gain | 0 (0) | 0 (0) | 10 (10.3) | 3 (15.0) |
| Adverse events, n (%) . | HD-DXM . | PDN . | ||
|---|---|---|---|---|
| Total (n = 95) . | ≥60 y (n = 18) . | Total (n = 97) . | ≥60 y (n = 20) . | |
| ALT | 1 (1.1) | 0 (0) | 0 (0) | 0 (0) |
| Arthralgia | 0 (0) | 0 (0) | 2 (2.1) | 1 (5.0) |
| Cushingoid appearance | 0 (0) | 0 (0) | 13 (13.4) | 2 (10.0) |
| Diarrhea | 0 (0) | 0 (0) | 1 (1.0) | 0 (0) |
| Dizziness | 2 (2.1) | 1 (5.6) | 5 (5.2) | 2 (10.0) |
| Edema | 0 (0) | 0 (0) | 4 (4.1) | 2 (10.0) |
| Fatigue | 1 (1.1) | 0 (0) | 4 (4.1) | 1 (5.0) |
| Fever | 1 (1.1) | 0 (0) | 0 (0) | 0 (0) |
| Hyperglycemia | 4 (4.2) | 1 (5.6) | 6 (6.2) | 3 (15.0) |
| Hypertension | 4 (4.2) | 2 (11.1) | 8 (8.2) | 3 (15.0) |
| Infection | 0 (0) | 0 (0) | 3 (3.1) | 1 (5.0) |
| Insomnia | 8 (8.4) | 3 (16.7) | 5 (5.2) | 2 (10.0) |
| Mood disorders | 7 (7.4) | 2 (11.1) | 4 (4.1) | 1 (5.0) |
| Nausea | 2 (2.1) | 1 (5.6) | 3 (3.1) | 1 (5.0) |
| Palpitation | 2 (2.1) | 1 (5.6) | 1 (1.0) | 0 (0) |
| Peptic ulcer | 2 (2.1) | 0 (0) | 5 (5.2) | 1 (5.0) |
| Weight gain | 0 (0) | 0 (0) | 10 (10.3) | 3 (15.0) |
ALT, alanine aminotransferase.