Table 1 Selected clinical studies with... | American Society of Hematology

Table 1

Selected clinical studies with single-agent chemotherapy in patients with relapsed/refractory cHL

Agent	No. of Patients	Prior ASCT	Response, %	PFS, mo	Reference
Gemcitabine	27	18	ORR, 22	6.4	37
			PR, 22		38
					39
Vinblastine	17	17	ORR, 59	EFS, 8.3	40
			CR, 12
			PR, 47
Vinorelbine	24	NR	ORR, 50	6	41
			CR, 14
			PR, 36
Bendamustine	34	26	ORR, 53	5.2	42
			CR, 33
			PR, 20
Liposomal doxorubicin	47	31	ORR, 72	NR	43
			CR, 51
			PR, 21

Agent	No. of Patients	Prior ASCT	Response, %	PFS, mo	Reference
Gemcitabine	27	18	ORR, 22	6.4	37
			PR, 22		38
					39
Vinblastine	17	17	ORR, 59	EFS, 8.3	40
			CR, 12
			PR, 47
Vinorelbine	24	NR	ORR, 50	6	41
			CR, 14
			PR, 36
Bendamustine	34	26	ORR, 53	5.2	42
			CR, 33
			PR, 20
Liposomal doxorubicin	47	31	ORR, 72	NR	43
			CR, 51
			PR, 21

Other agents with single-agent activity in cHL include chlorambucil, vincristine, etoposide, cyclophosphamide.

NR, not reported.