Comparison of VWF phenotypes between individual assay components
| Individual VWF activity test and variant VWD phenotype ratio comparison . | P . |
|---|---|
| VWF:GPIbM ratio [VWF:GPIbM/VWF:Ag]subject/[VWF:GPIbM/VWF:Ag]standard | |
| Type 2A ↓ ratio than type 1C | <.001 |
| Type 1 ↓ ratio than type 2B | <.001 |
| Type 2A ↓ ratio than type 2B | <.001 |
| VWF:FVIIIB ratio [VWF:FVIIIB/VWF:Ag]subject/[VWF:FVIIIB/VWF:Ag]standard | |
| Type 2N and 2N carriers ↓ ratio than HA (mild or carriers) | <.001 |
| VWF:CB3 ratio [VWF:CB3/VWF:Ag]subject/[VWF:CB3/VWF:Ag]standard | |
| Type 2A ↓ ratio than type 1C | <.001 |
| Type 2A ↓ ratio than type 2M | <.001 |
| VWFpp ratio [VWFpp/VWF:Ag]subject/[VWFpp/VWF:Ag]standard | |
| Type 2A ↓ ratio than type 1C | .002 |
| Type 1 ↓ ratio than type 1C | <.001 |
| VWF:Ag ratio [VWF:Ag]subject/[VWF:Ag]standard | |
| Type 1C ↓ ratio than type 2A | <.001 |
| Individual VWF activity test and variant VWD phenotype ratio comparison . | P . |
|---|---|
| VWF:GPIbM ratio [VWF:GPIbM/VWF:Ag]subject/[VWF:GPIbM/VWF:Ag]standard | |
| Type 2A ↓ ratio than type 1C | <.001 |
| Type 1 ↓ ratio than type 2B | <.001 |
| Type 2A ↓ ratio than type 2B | <.001 |
| VWF:FVIIIB ratio [VWF:FVIIIB/VWF:Ag]subject/[VWF:FVIIIB/VWF:Ag]standard | |
| Type 2N and 2N carriers ↓ ratio than HA (mild or carriers) | <.001 |
| VWF:CB3 ratio [VWF:CB3/VWF:Ag]subject/[VWF:CB3/VWF:Ag]standard | |
| Type 2A ↓ ratio than type 1C | <.001 |
| Type 2A ↓ ratio than type 2M | <.001 |
| VWFpp ratio [VWFpp/VWF:Ag]subject/[VWFpp/VWF:Ag]standard | |
| Type 2A ↓ ratio than type 1C | .002 |
| Type 1 ↓ ratio than type 1C | <.001 |
| VWF:Ag ratio [VWF:Ag]subject/[VWF:Ag]standard | |
| Type 1C ↓ ratio than type 2A | <.001 |
The ratio of each VWF activity test to VWF:Ag was evaluated for the ability to discriminate between VWF phenotypes.