Cox regression analysis of factors associated with CNS relapse in ABC and non-GCB subtypes
| Factor . | HR (95% CI) . | P . |
|---|---|---|
| ABC Dual expresser MYC+BCL2+ CNS-IPI high risk (≥4) | — 3.68 (1.27-10.64) 5.21 (1.03-26.30) | .281 .016 .046 |
| Non-GCB Dual expresser MYC+BCL2+ CNS-IPI high risk (≥4) | — 3.85 (1.38-10.70) 4.87 (.97-24.50) | .372 .010 .055 |
| Factor . | HR (95% CI) . | P . |
|---|---|---|
| ABC Dual expresser MYC+BCL2+ CNS-IPI high risk (≥4) | — 3.68 (1.27-10.64) 5.21 (1.03-26.30) | .281 .016 .046 |
| Non-GCB Dual expresser MYC+BCL2+ CNS-IPI high risk (≥4) | — 3.85 (1.38-10.70) 4.87 (.97-24.50) | .372 .010 .055 |
Cox regression analysis performed with either ABC (by Lymph2Cx) or non-GCB (by Hans algorithim) in the model. Data represent COO in DLBCL according to ABC vs GCB by Lymph2Cx and non-GCB vs GCB by Hans IHC algorithm.
CI, confidence interval; HR, hazard ratio.