Table 1

Association between demographic and clinical characteristics to VTE risk in each cohort

CharacteristicDiscovery cohortReplication cohort
Cases (n = 146)Controls (n = 432)PCases (n = 94)Controls (n = 65)P
Age, y* 54.9 ± 16.9 59.3 ± 10.9 .004 58.6 ± 16.7 64.9 ± 16.0 .02 
Height, cm* 167.3 ± 10.8 168.1 ± 9.8 .61 171.8 ± 12.3 170.2 ± 10.2 .41 
Weight, kg* 93.3 ± 28.9 87.4 ± 23.4 .22 99.9 ± 33.4 100.0 ± 34.1 .99 
West African Ancestry, % 81 80 .54 77 76 .33 
Sex, %       
 Female 73.3 70.4 .77 45.7 45.2 .82 
 Male 26.7 29.5 54.3 54.8 
VTE location in cases, %       
 DVT 51   47   
 PE   36   
 DVT/PE 24   17   
CharacteristicDiscovery cohortReplication cohort
Cases (n = 146)Controls (n = 432)PCases (n = 94)Controls (n = 65)P
Age, y* 54.9 ± 16.9 59.3 ± 10.9 .004 58.6 ± 16.7 64.9 ± 16.0 .02 
Height, cm* 167.3 ± 10.8 168.1 ± 9.8 .61 171.8 ± 12.3 170.2 ± 10.2 .41 
Weight, kg* 93.3 ± 28.9 87.4 ± 23.4 .22 99.9 ± 33.4 100.0 ± 34.1 .99 
West African Ancestry, % 81 80 .54 77 76 .33 
Sex, %       
 Female 73.3 70.4 .77 45.7 45.2 .82 
 Male 26.7 29.5 54.3 54.8 
VTE location in cases, %       
 DVT 51   47   
 PE   36   
 DVT/PE 24   17   
*

Values are mean ± standard deviation.

Association between sex and risk of VTE excluded DCPC controls.

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