Table 3 CFU-C number per E9-E10 Gata2-... | American Society of Hematology

Table 3

CFU-C number per E9-E10 Gata2-deleted hematopoietic tissues

Tissue	Stage	Genotype
Tissue	Stage	WT		Gata2^+/−		Gata2^−/−
AGM	E9, 20-23sp	8.5 ± 2.3	n = 1, 4	2.25 ± 0.9*	n = 1, 4	3.0 ± 1.0	n = 1, 2
	E10, 28-34sp	62.4 ± 20.8	n = 3, 7	24.0 ± 7.4*	n = 3, 13	16.7 ± 6.8*	n = 3, 9
VA+UA	E9, 20-23sp	7.0 ± 0.6	n = 1, 4	2.25 ± 0.6*	n = 1, 4	5.0 ± 2.0	n = 1, 2
	E10, 28-34sp	241.1 ± 67.8	n = 3, 7	78.7 ± 12.3**	n = 3, 13	12.0 ± 2.5**	n = 3, 9
YS	E9, 20-23sp	772.5 ± 85.3	n = 1, 4	500.0 ± 71.5*	n = 1, 4	64.4 ± 12.2**	n = 1, 2
	E10, 28-34sp	918.6 ± 147.9	n = 3, 7	584.6 ± 89.0**	n = 3, 9	25.7 ± 8.0**	n = 2, 3
		*Gata2^f/+or Gata2*^f/f		*VEC-Cre:Gata2*^f/+		*VEC-Cre:Gata2*^−/−
FL	E10, 30-34sp	115.8 ± 35.0	n = 2, 5	83.0 ± 20.8	n = 2, 6	22.2 ± 6.7*	n = 2, 6
PL	E10, 30-34sp	406.0 ± 134.0	n = 2, 5	81.0 ± 25.0*	n = 2, 6	12.0 ± 4.0*	n = 2, 6

Tissue	Stage	Genotype
Tissue	Stage	WT		Gata2^+/−		Gata2^−/−
AGM	E9, 20-23sp	8.5 ± 2.3	n = 1, 4	2.25 ± 0.9*	n = 1, 4	3.0 ± 1.0	n = 1, 2
	E10, 28-34sp	62.4 ± 20.8	n = 3, 7	24.0 ± 7.4*	n = 3, 13	16.7 ± 6.8*	n = 3, 9
VA+UA	E9, 20-23sp	7.0 ± 0.6	n = 1, 4	2.25 ± 0.6*	n = 1, 4	5.0 ± 2.0	n = 1, 2
	E10, 28-34sp	241.1 ± 67.8	n = 3, 7	78.7 ± 12.3**	n = 3, 13	12.0 ± 2.5**	n = 3, 9
YS	E9, 20-23sp	772.5 ± 85.3	n = 1, 4	500.0 ± 71.5*	n = 1, 4	64.4 ± 12.2**	n = 1, 2
	E10, 28-34sp	918.6 ± 147.9	n = 3, 7	584.6 ± 89.0**	n = 3, 9	25.7 ± 8.0**	n = 2, 3
		*Gata2^f/+or Gata2*^f/f		*VEC-Cre:Gata2*^f/+		*VEC-Cre:Gata2*^−/−
FL	E10, 30-34sp	115.8 ± 35.0	n = 2, 5	83.0 ± 20.8	n = 2, 6	22.2 ± 6.7*	n = 2, 6
PL	E10, 30-34sp	406.0 ± 134.0	n = 2, 5	81.0 ± 25.0*	n = 2, 6	12.0 ± 4.0*	n = 2, 6

Number of total CFU-C (mean ± SEM) per tissue shown for WT, Gata2 germline, and conditional knockout embryos at E9 and E10.

P < .05.

P < .01.