Table 2

Polysome-enriched transcripts identified as increasing in megakaryocytes during proplatelet formation by polysome profiling

Proteins that correspond to isolated and sequenced mRNA transcripts (protein symbol)Round MK (polysome)Proplt MK (polysome)Ratio (proplt/round)
Myristoylated alanine-rich C-kinase substrate (MARCKS) 4.33 24.58 5.68 
Tubulin, β 2B class IIb (TUBB2B) 33.60 139.47 4.15 
BCL2-like 11 (BCL2l11) 17.54 84.12 4.80 
BCL2 binding component 3 (BBC3) 105.51 504.99 4.97 
Kruppel-like factor 10 (KLF10) 4.99 24.33 4.87 
Interleukin 15 (IL15) 13.12 72.22 5.50 
Vascular endothelial growth factor C (VEGFC) 5.98 35.51 5.93 
Chemokine (C-C motif) ligand 5/RANTES (CCL5) 4.40 88.57 20.12 
Active BCR-related (ABR) 3.69 19.46 5.27 
Histone cluster 1, H4h (HIST1H4H) 16.21 155.65 9.60 
Growth arrest and DNA-damage-inducible (GADD45B) 13.20 197.18 14.93 
Proteins that correspond to isolated and sequenced mRNA transcripts (protein symbol)Round MK (polysome)Proplt MK (polysome)Ratio (proplt/round)
Myristoylated alanine-rich C-kinase substrate (MARCKS) 4.33 24.58 5.68 
Tubulin, β 2B class IIb (TUBB2B) 33.60 139.47 4.15 
BCL2-like 11 (BCL2l11) 17.54 84.12 4.80 
BCL2 binding component 3 (BBC3) 105.51 504.99 4.97 
Kruppel-like factor 10 (KLF10) 4.99 24.33 4.87 
Interleukin 15 (IL15) 13.12 72.22 5.50 
Vascular endothelial growth factor C (VEGFC) 5.98 35.51 5.93 
Chemokine (C-C motif) ligand 5/RANTES (CCL5) 4.40 88.57 20.12 
Active BCR-related (ABR) 3.69 19.46 5.27 
Histone cluster 1, H4h (HIST1H4H) 16.21 155.65 9.60 
Growth arrest and DNA-damage-inducible (GADD45B) 13.20 197.18 14.93 
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