Hematologic parameters from Het or low TF mice transplanted with BM from WT or BERK (sickle) mice
| Variable . | WTBM/Het . | WTBM/low TF . | BERKBM/Het . | BERKBM/low TF . |
|---|---|---|---|---|
| RBC, 106/µL | 8.1 ± 0.2 | 7.8 ± 0.7 | 5.9 ± 0.2*** | 5.9 ± 0.3*** |
| Hemoglobin, g/dL | 8.9 ± 0.6 | 8.2 ± 1.1 | 5.8 ± 0.5*** | 5.9 ± 0.4* |
| Hematocrit, % | 32.1 ± 0.3 | 33.1 ± 0.9 | 26.9 ± 0.8*** | 27.5 ± 0.8*** |
| MCV, fL | 39.9 ± 0.9 | 40.4 ± 1.8 | 45.5 ± 0.6*** | 46.8 ± 0.9*** |
| LDH, IU/L | 51.7 ± 4.3 | 54.9 ± 6.2 | 79.4 ± 7.2* | 75.9 ± 8.1 |
| WBC, 103/µL | 11.8 ± 1.0 | 8.6 ± 0.8 | 19.7 ± 1.7*** | 16.7 ± 1.3*** |
| Platelets, 103/µL | 699.4 ± 24.5 | 682.4 ± 48.8 | 754.4 ± 41.13 | 812.4 ± 34.2 |
| Variable . | WTBM/Het . | WTBM/low TF . | BERKBM/Het . | BERKBM/low TF . |
|---|---|---|---|---|
| RBC, 106/µL | 8.1 ± 0.2 | 7.8 ± 0.7 | 5.9 ± 0.2*** | 5.9 ± 0.3*** |
| Hemoglobin, g/dL | 8.9 ± 0.6 | 8.2 ± 1.1 | 5.8 ± 0.5*** | 5.9 ± 0.4* |
| Hematocrit, % | 32.1 ± 0.3 | 33.1 ± 0.9 | 26.9 ± 0.8*** | 27.5 ± 0.8*** |
| MCV, fL | 39.9 ± 0.9 | 40.4 ± 1.8 | 45.5 ± 0.6*** | 46.8 ± 0.9*** |
| LDH, IU/L | 51.7 ± 4.3 | 54.9 ± 6.2 | 79.4 ± 7.2* | 75.9 ± 8.1 |
| WBC, 103/µL | 11.8 ± 1.0 | 8.6 ± 0.8 | 19.7 ± 1.7*** | 16.7 ± 1.3*** |
| Platelets, 103/µL | 699.4 ± 24.5 | 682.4 ± 48.8 | 754.4 ± 41.13 | 812.4 ± 34.2 |
Asterisks indicate statistical significance compared with WTBM within the same TF genotype. Data were analyzed by 2-way analysis of variance and Bonferroni post-hoc analysis.
LDH, lactate dehydrogenase; MCV, mean corpuscular volume; RBC, red blood cells; WBC, white blood cells.
*P > .05; ***P > .001.