Composite karyotypes from representative tumor samples
| Mouse ID . | Genotype . | Pathology . | JH4 intron . | Spectral karyotype . |
|---|---|---|---|---|
| 340 | IµHABcl6 | DLBCL | M | 40∼43 < 2n>,XX,+8[11],+8x2[6],Der(10)T(10A4;13?A)T(13?B;17D)[3],+15[19],Der(17) T(10A4;17D)[3][cp21] / 84∼88 < 4n>,XXXX,+8x2∼6[4],+15x2[4][cp4] |
| 379 | IµHABcl6 | DLBCL | M | 42∼44 < 2n>,X,-X[14],Del(X?A6)[5],Dp(5)[14],Der(10)[3],+13[7],+13x2[2],+15[17],+15x2[2],+16[12],+16x2[2],+19 [19][cp19] / 84∼89 < 4n>,XX or XXX,-X[2],-Xx2[4],Dp(5)x2[6],+15x2[3],+15x3[3],+16x2[5],+16x4[1],+19x2[6][cp6] |
| 438 | IµHABcl6 | DLBCL | UM | 40∼42 < 2n>,XY,Del(2G)[3],Der(4)T(4E2;13A3)[3],+13[1],+15[3],+16[4],+17[3][cp24] / 84 < 4n>,XXYY,Der(4)T(4E2;13A3)x2,+13,+15,+16,+16[cp1] |
| 167 | IµHABcl6 Ung−/−Msh2−/− | DLBCL | M | 40∼41,XX,T(2C2;17A2)[21],+15[2],+19[10][cp30] |
| 375 | IµHABcl6 Ung−/−Msh2−/− | DLBCL | M | 40,XY,Dp(1E-F)[2][cp30] |
| 414 | IµHABcl6 Ung−/−Msh2−/− | DLBCL | M | 40,XX[5] / 40∼42,XX,T(8E1;13A3)[2],Der(10)?Del(10D)Dp(10A-C)[3],Der(10)Dp(10A-C)T(10C;16C2)[22],+15[5],+Der(15)T(10D;15D1)[21][cp34] / 79∼83 < 4n>,XXXX,Der(10)?Del(10D)Dp(10A-C)x2[1],Der(10)Dp(10A-C)T(10C;16C2)[1],+15x2[2],+Der(15)T(10D;15D1)x2[1][cp6] |
| 491 | IµHABcl6 Ung−/−Msh2−/− | DLBCL | M | 40,XX,+Rb(XA1.7A1)[30][cp30] |
| 448 | IµHABcl6 Ung−/− | FL | M | 41 < 2n>,X,-X[30],+15[30],+17[30][cp30] |
| 496 | IµHABcl6 Ung−/− | FL | M | 40∼43 < 2n>,XY,+Y[2],+2[6],+5[2],Del(6B3-E1)[24],+15[20],+17[11],+mar[3][cp30] |
| Mouse ID . | Genotype . | Pathology . | JH4 intron . | Spectral karyotype . |
|---|---|---|---|---|
| 340 | IµHABcl6 | DLBCL | M | 40∼43 < 2n>,XX,+8[11],+8x2[6],Der(10)T(10A4;13?A)T(13?B;17D)[3],+15[19],Der(17) T(10A4;17D)[3][cp21] / 84∼88 < 4n>,XXXX,+8x2∼6[4],+15x2[4][cp4] |
| 379 | IµHABcl6 | DLBCL | M | 42∼44 < 2n>,X,-X[14],Del(X?A6)[5],Dp(5)[14],Der(10)[3],+13[7],+13x2[2],+15[17],+15x2[2],+16[12],+16x2[2],+19 [19][cp19] / 84∼89 < 4n>,XX or XXX,-X[2],-Xx2[4],Dp(5)x2[6],+15x2[3],+15x3[3],+16x2[5],+16x4[1],+19x2[6][cp6] |
| 438 | IµHABcl6 | DLBCL | UM | 40∼42 < 2n>,XY,Del(2G)[3],Der(4)T(4E2;13A3)[3],+13[1],+15[3],+16[4],+17[3][cp24] / 84 < 4n>,XXYY,Der(4)T(4E2;13A3)x2,+13,+15,+16,+16[cp1] |
| 167 | IµHABcl6 Ung−/−Msh2−/− | DLBCL | M | 40∼41,XX,T(2C2;17A2)[21],+15[2],+19[10][cp30] |
| 375 | IµHABcl6 Ung−/−Msh2−/− | DLBCL | M | 40,XY,Dp(1E-F)[2][cp30] |
| 414 | IµHABcl6 Ung−/−Msh2−/− | DLBCL | M | 40,XX[5] / 40∼42,XX,T(8E1;13A3)[2],Der(10)?Del(10D)Dp(10A-C)[3],Der(10)Dp(10A-C)T(10C;16C2)[22],+15[5],+Der(15)T(10D;15D1)[21][cp34] / 79∼83 < 4n>,XXXX,Der(10)?Del(10D)Dp(10A-C)x2[1],Der(10)Dp(10A-C)T(10C;16C2)[1],+15x2[2],+Der(15)T(10D;15D1)x2[1][cp6] |
| 491 | IµHABcl6 Ung−/−Msh2−/− | DLBCL | M | 40,XX,+Rb(XA1.7A1)[30][cp30] |
| 448 | IµHABcl6 Ung−/− | FL | M | 41 < 2n>,X,-X[30],+15[30],+17[30][cp30] |
| 496 | IµHABcl6 Ung−/− | FL | M | 40∼43 < 2n>,XY,+Y[2],+2[6],+5[2],Del(6B3-E1)[24],+15[20],+17[11],+mar[3][cp30] |
[ ], cell number analyzed; cp, composite; Del, deletion; Der, derivative chromosome; Der(N)T, nonreciprocal translocation; Dp, duplication; M, mutated; mar, marker chromosome; Rb, Robertsonian translocation; T, reciprocal translocation; UM, unmutated.