Sequence and cleavage sites of granzyme and caspase biosensors
| Sensor name . | Predicted cleavage site . | Protease(s) predicted to cleave site . |
|---|---|---|
| GLS.IEAD | SGRIEADSESL | Granzyme B; caspase 10 |
| GLS.IETD | SGIETDSGSL | Granzyme B; caspase 8 |
| GLS.VGPD | SKSVGPDFGSL | Granzyme B |
| GLS.DEVD | SDEVDGSL | Caspase 3/7 |
| GLS.SGR | GSSGRSGSL | Granzyme A; granzyme K |
| GLS.PGPR | GSPGPREGSL | Granzyme A; granzyme K |
| GLS.QGPR | GSQGPRGSL | Granzyme A; granzyme K |
| Sensor name . | Predicted cleavage site . | Protease(s) predicted to cleave site . |
|---|---|---|
| GLS.IEAD | SGRIEADSESL | Granzyme B; caspase 10 |
| GLS.IETD | SGIETDSGSL | Granzyme B; caspase 8 |
| GLS.VGPD | SKSVGPDFGSL | Granzyme B |
| GLS.DEVD | SDEVDGSL | Caspase 3/7 |
| GLS.SGR | GSSGRSGSL | Granzyme A; granzyme K |
| GLS.PGPR | GSPGPREGSL | Granzyme A; granzyme K |
| GLS.QGPR | GSQGPRGSL | Granzyme A; granzyme K |