Effect of LCN2 on the genotype of MF hematopoietic colonies
| Case . | JAK2 genotype of hematopoietic colonies . | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Control . | LCN2 20 ng/mL . | LCN2 100 ng/mL . | |||||||
| Homo . | Hete . | Wild-type . | Homo . | Hete . | Wild-type . | Homo . | Hete . | Wild-type . | |
| MF 1 | 0 (0) | 24 (100) | 0 (0) | 14 (61) | 9 (39) | 0 (0) | 13 (57) | 10 (43) | 0 (0) |
| MF 2 | 10 (43.5) | 13 (56.5) | 0 (0) | 4 (17) | 16 (67) | 4 (17) | 8 (33) | 16 (67) | 0 (0) |
| MF 3 | 11 (52) | 9 (43) | 1 (5) | 18 (100) | 0 (0) | 0 (0) | 24 (100) | 0 (0) | 0 (0) |
| MF 4 | 0 (0) | 12 (50) | 12 (50) | 8 (35.3) | 7 (29.4) | 8 (35.3) | 14 (64) | 6 (27) | 2 (9) |
| Case . | JAK2 genotype of hematopoietic colonies . | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Control . | LCN2 20 ng/mL . | LCN2 100 ng/mL . | |||||||
| Homo . | Hete . | Wild-type . | Homo . | Hete . | Wild-type . | Homo . | Hete . | Wild-type . | |
| MF 1 | 0 (0) | 24 (100) | 0 (0) | 14 (61) | 9 (39) | 0 (0) | 13 (57) | 10 (43) | 0 (0) |
| MF 2 | 10 (43.5) | 13 (56.5) | 0 (0) | 4 (17) | 16 (67) | 4 (17) | 8 (33) | 16 (67) | 0 (0) |
| MF 3 | 11 (52) | 9 (43) | 1 (5) | 18 (100) | 0 (0) | 0 (0) | 24 (100) | 0 (0) | 0 (0) |
| MF 4 | 0 (0) | 12 (50) | 12 (50) | 8 (35.3) | 7 (29.4) | 8 (35.3) | 14 (64) | 6 (27) | 2 (9) |
Twenty-four colonies were randomly selected for each condition. Values are represented as raw data (% of total).
Homo: homozygous; Hete: heterozygous.