Summary of peripheral B-cell development in wild-type, Relb−/−, cRel−/−, and Relb−/−cRel−/− mice
| Phenotype . | Total B cells (×106) . | |||
|---|---|---|---|---|
| wild-type . | Relb−/− . | cRel−/− . | Relb−/−cRel−/− . | |
| Total cells | 75.4 ± 17 | 131 ± 15** | 76.1 ± 8.3 | 104 ± 25* |
| Total B cells | 51.3 ± 6.9 | 39.8 ± 8.6* | 41.6 ± 4.9 | 29.1 ± 7.8*** |
| Mature | 32.8 ± 6.7 | 23.3 ± 7.1* | 30.1 ± 4.4 | 14.3 ± 4.2* |
| Transitional | 9.28 ± 1.9 | 7.85 ± 1.7 | 9.86 ± 2.5 | 12.7 ± 2.7* |
| T1 | 3.00 ± 1.2 | 3.17 ± 1.2 | 3.58 ± 0.94 | 6.30 ± 2.0** |
| T2 | 5.42 ± 0.64 | 5.21 ± 2.0 | 5.54 ± 1.3 | 6.48 ± 2.5 |
| MZ | 3.1 ± 1.1 | 0.067 ± 0.052**** | 3.2 ± 0.071 | 0.31 ± 0.34**** |
| Follicular | 25.3 ± 6.3 | 22.4 ± 5.1 | 24.1 ± 4.4 | 12.5 ± 3.6*** |
| Phenotype . | Total B cells (×106) . | |||
|---|---|---|---|---|
| wild-type . | Relb−/− . | cRel−/− . | Relb−/−cRel−/− . | |
| Total cells | 75.4 ± 17 | 131 ± 15** | 76.1 ± 8.3 | 104 ± 25* |
| Total B cells | 51.3 ± 6.9 | 39.8 ± 8.6* | 41.6 ± 4.9 | 29.1 ± 7.8*** |
| Mature | 32.8 ± 6.7 | 23.3 ± 7.1* | 30.1 ± 4.4 | 14.3 ± 4.2* |
| Transitional | 9.28 ± 1.9 | 7.85 ± 1.7 | 9.86 ± 2.5 | 12.7 ± 2.7* |
| T1 | 3.00 ± 1.2 | 3.17 ± 1.2 | 3.58 ± 0.94 | 6.30 ± 2.0** |
| T2 | 5.42 ± 0.64 | 5.21 ± 2.0 | 5.54 ± 1.3 | 6.48 ± 2.5 |
| MZ | 3.1 ± 1.1 | 0.067 ± 0.052**** | 3.2 ± 0.071 | 0.31 ± 0.34**** |
| Follicular | 25.3 ± 6.3 | 22.4 ± 5.1 | 24.1 ± 4.4 | 12.5 ± 3.6*** |
****P < .0001, ***P < .001, **P < .01, *P < .05.