Baseline 18FDG-PET parameters
Parameter . | Median . | Interquartile range . | ROC curve for PFS . | ROC curve for OS . | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
AUC (95% CI) . | P . | Cutoff . | Sensitivity (95% CI) . | Specificity (95% CI) . | AUC (95% CI) . | P . | Cutoff . | Sensitivity (95% CI) . | Specificity (95% CI) . | |||
SUVmax | 18.8 | 15.5-23 | 0.647 (0.476-0.819) | .09 | 22.2 | 61.5% (31.6-86.1) | 75.6% (65.4-84.0) | 0.711 (0.488-0.935) | .06 | 22.2 | 83.3% (35.9-99.6) | 74.2% (64.3-92.6) |
MTV | 406 | 267-641 | 0.814 (0.681 -0.946) | .0001 | 703 | 69% (38.6-90.9) | 87.8% (79.2-93.7) | 0.812 (0.661-0.941) | .0001 | 490 | 100% (54.1-100) | 60.8% (50.4-70.6) |
TLG | 4261 | 2363-6398 | 0.867 (0.746-1.0) | .0001 | 5814 | 92.1% (64.0-99.8) | 77.7% (66.6-84.9) | 0.921 (0.841-1.0) | .0001 | 6031 | 100% (54.1-100) | 74.2% (64.3-82.6) |
Parameter . | Median . | Interquartile range . | ROC curve for PFS . | ROC curve for OS . | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
AUC (95% CI) . | P . | Cutoff . | Sensitivity (95% CI) . | Specificity (95% CI) . | AUC (95% CI) . | P . | Cutoff . | Sensitivity (95% CI) . | Specificity (95% CI) . | |||
SUVmax | 18.8 | 15.5-23 | 0.647 (0.476-0.819) | .09 | 22.2 | 61.5% (31.6-86.1) | 75.6% (65.4-84.0) | 0.711 (0.488-0.935) | .06 | 22.2 | 83.3% (35.9-99.6) | 74.2% (64.3-92.6) |
MTV | 406 | 267-641 | 0.814 (0.681 -0.946) | .0001 | 703 | 69% (38.6-90.9) | 87.8% (79.2-93.7) | 0.812 (0.661-0.941) | .0001 | 490 | 100% (54.1-100) | 60.8% (50.4-70.6) |
TLG | 4261 | 2363-6398 | 0.867 (0.746-1.0) | .0001 | 5814 | 92.1% (64.0-99.8) | 77.7% (66.6-84.9) | 0.921 (0.841-1.0) | .0001 | 6031 | 100% (54.1-100) | 74.2% (64.3-82.6) |