Patient clinical characteristics at presentation
| Characteristic (n = 103 unless otherwise specified) . | No. (%) of patients . |
|---|---|
| Age | |
| Median (interquartile range), y | 33 (26-41) |
| ≤60 y | 97 (94) |
| Female sex | 63 (61) |
| Performance status | |
| ECOG 0-1 | 88 (85) |
| ECOG >1 | 15 (15) |
| B-symptoms at presentation | 38 (37) |
| Bulky disease | |
| Max mediastinal lesion >7 cm | 89 (86) |
| Max mediastinal lesion >10 cm | 54 (52) |
| Extramediastinal involvement ≥1 site | 14 (14) |
| Bone marrow involvement | 2 (2) |
| Ann Arbor stage | |
| I-II | 97 (94) |
| III-IV | 6 (6) |
| LDH >normal upper value* | 77 (75) |
| IPI | |
| Low and low-intermediate risk | 99 (96) |
| Intermediate-high and high risk | 4 (4) |
| aaIPI (n = 97) | |
| Low and low-intermediate risk | 82 (85) |
| Intermediate-high and high risk | 15 (15) |
| Front-line treatment | |
| R-CHOP or R-CHOP like regimen* | 16 (16) |
| R-VACOP-B or R-MACOP-B regimen* | 87 (84) |
| RT | 93 (90) |
| Characteristic (n = 103 unless otherwise specified) . | No. (%) of patients . |
|---|---|
| Age | |
| Median (interquartile range), y | 33 (26-41) |
| ≤60 y | 97 (94) |
| Female sex | 63 (61) |
| Performance status | |
| ECOG 0-1 | 88 (85) |
| ECOG >1 | 15 (15) |
| B-symptoms at presentation | 38 (37) |
| Bulky disease | |
| Max mediastinal lesion >7 cm | 89 (86) |
| Max mediastinal lesion >10 cm | 54 (52) |
| Extramediastinal involvement ≥1 site | 14 (14) |
| Bone marrow involvement | 2 (2) |
| Ann Arbor stage | |
| I-II | 97 (94) |
| III-IV | 6 (6) |
| LDH >normal upper value* | 77 (75) |
| IPI | |
| Low and low-intermediate risk | 99 (96) |
| Intermediate-high and high risk | 4 (4) |
| aaIPI (n = 97) | |
| Low and low-intermediate risk | 82 (85) |
| Intermediate-high and high risk | 15 (15) |
| Front-line treatment | |
| R-CHOP or R-CHOP like regimen* | 16 (16) |
| R-VACOP-B or R-MACOP-B regimen* | 87 (84) |
| RT | 93 (90) |
RT, consolidation mediastinal radiotherapy.
Details on the immunochemotherapy regimens and radiotherapy plans have been previously reported.8