Causes of death in the 2 groups
. | Use of ATG . | P* . | |
---|---|---|---|
No . | Yes . | ||
Relapse or progression, n (%) | 158 (27) | 20 (24) | .58 |
Cause of NRM, n (%) | 148 (25) | 37 (45) | .0002 |
Infections | 76 (13.1) | 23 (28) | .0013 |
Bacterial | 26 (4.5) | 5 (6.1) | |
Viral | 18 (3.1) | 6 (7.3) | |
Parasitical | 4 (0.7) | 3 (3.7) | |
Fungal | 12 (2.1) | 2 (2.4) | |
Unknown | 16 (2.8) | 7 (8.5) | .016 |
PTLD | 3 (0.5) | 5 (6.1) | .001 |
Pulmonary toxicity | 2 (0.3) | 2 (2.4) | |
CNS toxicity | 9 (6.1) | 1 | |
GVHD | 25 (16.9) | 2 | .56 |
Hemorrhage | 4 | — | |
Multiorgan failure | 5 | — | |
Renal toxicity | 3 | — |
. | Use of ATG . | P* . | |
---|---|---|---|
No . | Yes . | ||
Relapse or progression, n (%) | 158 (27) | 20 (24) | .58 |
Cause of NRM, n (%) | 148 (25) | 37 (45) | .0002 |
Infections | 76 (13.1) | 23 (28) | .0013 |
Bacterial | 26 (4.5) | 5 (6.1) | |
Viral | 18 (3.1) | 6 (7.3) | |
Parasitical | 4 (0.7) | 3 (3.7) | |
Fungal | 12 (2.1) | 2 (2.4) | |
Unknown | 16 (2.8) | 7 (8.5) | .016 |
PTLD | 3 (0.5) | 5 (6.1) | .001 |
Pulmonary toxicity | 2 (0.3) | 2 (2.4) | |
CNS toxicity | 9 (6.1) | 1 | |
GVHD | 25 (16.9) | 2 | .56 |
Hemorrhage | 4 | — | |
Multiorgan failure | 5 | — | |
Renal toxicity | 3 | — |
CNS: central nervous system; PTLD, posttransplant lymphoproliferative disorder.
The P value for overall causes of death is <.001 and was determined by Fisher’s exact test.