Table 2 Summary of serious adverse... | American Society of Hematology

Table 2

Summary of serious adverse events (≥2% of patients) regardless of attribution

	Total (N = 111)
SAE*, n (%)	Any grade	Grade 3-4	Grade 5
Disease progression†	11 (10%)	3 (3%)	8 (7%)
Pneumonia	8 (7%)	7 (6%)	1 (1%)
Atrial fibrillation	7 (6%)	6 (5%)‡	0
Urinary tract infection	4 (4%)	3 (3%)	0
Febrile neutropenia	3 (3%)	3 (3%)	0
Abdominal pain	3 (3%)	3 (3%)	0
Acute renal failure	3 (3%)	2 (2%)	1 (1%)
Subdural hematoma	3 (3%)	2 (2%)	0
Pyrexia	3 (3%)	1 (1%)	0
Confusional state	3 (3%)	1 (1%)	0

	Total (N = 111)
SAE*, n (%)	Any grade	Grade 3-4	Grade 5
Disease progression†	11 (10%)	3 (3%)	8 (7%)
Pneumonia	8 (7%)	7 (6%)	1 (1%)
Atrial fibrillation	7 (6%)	6 (5%)‡	0
Urinary tract infection	4 (4%)	3 (3%)	0
Febrile neutropenia	3 (3%)	3 (3%)	0
Abdominal pain	3 (3%)	3 (3%)	0
Acute renal failure	3 (3%)	2 (2%)	1 (1%)
Subdural hematoma	3 (3%)	2 (2%)	0
Pyrexia	3 (3%)	1 (1%)	0
Confusional state	3 (3%)	1 (1%)	0

SAEs were updated with an estimated median follow-up of 26.7 months.

Mantle cell lymphoma reported as a SAE by investigators.

One additional patient had a grade 3 atrial fibrillation that was not considered an SAE.