Clinical features of patients with myeloid neoplasms and ring sideroblasts included in the study
| Features . | . |
|---|---|
| No. of patients | 293 |
| Median age, (range), y | 70 (18-96) |
| Sex, M/F | 153/140 |
| Diagnosis | |
| MDS | 243 |
| RARS | 90 |
| RCMD-RS | 69 |
| RCUD (RA) | 7 |
| RCMD | 27 |
| MDS with isolated del(5q) | 7 |
| RAEB-1 | 20 |
| RAEB-2 | 23 |
| MDS/MPN | 50 |
| CMML | 9 |
| RARS-T | 41 |
| Median hemoglobin, (range), g/dL | 9.9 (5.6-15.8) |
| RBC transfusion dependency (%) | 108/293 (37) |
| Median WBC count, (range), ×109/L | 4.9 (1.0-13.9) |
| Median ANC, (range), ×109/L | 2.5 (0.1-12.9) |
| Median platelet count, (range), ×109/L | 263 (7-1130) |
| Median serum ferritin, (range), ng/mL | 541 (30-5745) |
| Median bone marrow blasts, (range), % | 2 (0-19) |
| Median bone marrow ring sideroblasts, (range), % | 32 (1-95) |
| Chromosomal abnormalities (%) | 83/277 (30) |
| Features . | . |
|---|---|
| No. of patients | 293 |
| Median age, (range), y | 70 (18-96) |
| Sex, M/F | 153/140 |
| Diagnosis | |
| MDS | 243 |
| RARS | 90 |
| RCMD-RS | 69 |
| RCUD (RA) | 7 |
| RCMD | 27 |
| MDS with isolated del(5q) | 7 |
| RAEB-1 | 20 |
| RAEB-2 | 23 |
| MDS/MPN | 50 |
| CMML | 9 |
| RARS-T | 41 |
| Median hemoglobin, (range), g/dL | 9.9 (5.6-15.8) |
| RBC transfusion dependency (%) | 108/293 (37) |
| Median WBC count, (range), ×109/L | 4.9 (1.0-13.9) |
| Median ANC, (range), ×109/L | 2.5 (0.1-12.9) |
| Median platelet count, (range), ×109/L | 263 (7-1130) |
| Median serum ferritin, (range), ng/mL | 541 (30-5745) |
| Median bone marrow blasts, (range), % | 2 (0-19) |
| Median bone marrow ring sideroblasts, (range), % | 32 (1-95) |
| Chromosomal abnormalities (%) | 83/277 (30) |
ANC, absolute neutrophil count; CMML, chronic myelomonocytic leukemia; F, female; M, male; MDS, myelodysplastic syndrome; MPN, myeloproliferative neoplasm; RA, refactory anemia; RAEB, refactory anemia with excell blasts; RARS, refractory anemia with ring sideroblasts; RARS-T, RARS associated with marked thrombocytosis; RBC, red blood cell; RCMD, refractory cytopenia with multilineage dysplasia; RCMD-RS, RCMD and ring sideroblasts; RCUD, refractory cytopenia with unilineage dysplasia; WBC, white blood cell.