Unadjusted effect of trisomies and hyperdiploidy on TTP and OS
| . | TTP . | OS . | ||
|---|---|---|---|---|
| HR (95% CI) . | P . | HR (95% CI) . | P . | |
| Trisomy 3 | 0.8 (0.7-0.9) | <.001 | 0.6 (0.5-0.8) | <.001 |
| Trisomy 5 | 0.8 (0.7-0.9) | .003 | 0.5 (0.4-0.7) | <.001 |
| Trisomy 7 | 0.8 (0.7-1.0) | .038 | 0.8 (0.6-1.0) | .030 |
| Trisomy 9 | 0.8 (0.7-1.0) | .018 | 0.6 (0.5-0.8) | <.001 |
| Trisomy 11 | 0.8 (0.7-0.9) | .001 | 0.6 (0.4-0.7) | <.001 |
| Trisomy 15 | 0.8 (0.7-0.9) | .003 | 0.6 (0.5-0.8) | <.001 |
| Trisomy 17 | 1.0 (0.7-1.3) | .752 | 1.0 (0.6-1.5) | .815 |
| Trisomy 18 | 1.0 (0.8-1.2) | .690 | 1.1 (0.8-1.5) | .683 |
| Trisomy 19 | 0.8 (0.7-1.0) | .008 | 0.6 (0.5-0.8) | <.001 |
| Trisomy 21 | 0.9 (0.8-1.1) | .282 | 1.0 (0.8-1.2) | .748 |
| At least one trisomy | 0.9 (0.8-1.0) | .075 | 0.7 (0.6-0.9) | .004 |
| Number of chromosomes | ||||
| 46 | 1 | .014 | 1 | |
| <46 | 1.3 (1.1-1.7) | .150 | 1.5 (1.1-2.1) | .014 |
| 47-50 | 1.2 (0.9-1.6) | 1.4 (0.9-2.0) | .113 | |
| ≥51 | 1.0 (0.8-1.2) | .710 | 0.7 (0.5-1.0) | .086 |
| . | TTP . | OS . | ||
|---|---|---|---|---|
| HR (95% CI) . | P . | HR (95% CI) . | P . | |
| Trisomy 3 | 0.8 (0.7-0.9) | <.001 | 0.6 (0.5-0.8) | <.001 |
| Trisomy 5 | 0.8 (0.7-0.9) | .003 | 0.5 (0.4-0.7) | <.001 |
| Trisomy 7 | 0.8 (0.7-1.0) | .038 | 0.8 (0.6-1.0) | .030 |
| Trisomy 9 | 0.8 (0.7-1.0) | .018 | 0.6 (0.5-0.8) | <.001 |
| Trisomy 11 | 0.8 (0.7-0.9) | .001 | 0.6 (0.4-0.7) | <.001 |
| Trisomy 15 | 0.8 (0.7-0.9) | .003 | 0.6 (0.5-0.8) | <.001 |
| Trisomy 17 | 1.0 (0.7-1.3) | .752 | 1.0 (0.6-1.5) | .815 |
| Trisomy 18 | 1.0 (0.8-1.2) | .690 | 1.1 (0.8-1.5) | .683 |
| Trisomy 19 | 0.8 (0.7-1.0) | .008 | 0.6 (0.5-0.8) | <.001 |
| Trisomy 21 | 0.9 (0.8-1.1) | .282 | 1.0 (0.8-1.2) | .748 |
| At least one trisomy | 0.9 (0.8-1.0) | .075 | 0.7 (0.6-0.9) | .004 |
| Number of chromosomes | ||||
| 46 | 1 | .014 | 1 | |
| <46 | 1.3 (1.1-1.7) | .150 | 1.5 (1.1-2.1) | .014 |
| 47-50 | 1.2 (0.9-1.6) | 1.4 (0.9-2.0) | .113 | |
| ≥51 | 1.0 (0.8-1.2) | .710 | 0.7 (0.5-1.0) | .086 |