Table 2

Analysis of postnatal survival comparing offspring with complete fibrinogen deficiency (Fib−/−) and mice homozygous for FibAEK

♀FibWT/Null × ♂FibNull/Null♀FibWT/AEK × ♂FibAEK/AEK
Offspring genotype FibWT/− Fib−/− FibWT/AEK FibAEK/AEK 
Mendelian ratio 
No. observed (at 3 weeks) 170 85 130 93 
% of expected* 100% 50% 100% 72% 
♀FibWT/Null × ♂FibNull/Null♀FibWT/AEK × ♂FibAEK/AEK
Offspring genotype FibWT/− Fib−/− FibWT/AEK FibAEK/AEK 
Mendelian ratio 
No. observed (at 3 weeks) 170 85 130 93 
% of expected* 100% 50% 100% 72% 
*

P < .05, χ2 analysis.

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