Mutational analysis of IgM VH regions in ATMKO.CD3εKO B-cell lymphomas
. | Tumor identification no. . | |||||
---|---|---|---|---|---|---|
12437 . | 16508 . | 25787 . | 39317 . | 178119 . | 180764 . | |
VDJ | J558.74.176, DFL16.1, JH4 | J558.54.148, DST4.2, JH4 | Vh10.2b, DSP2.2, JH1 | J558.66.165, DSP2.12, JH2 | J606.1.79, DFL16.1, JH3 | J558.16.106, DSP2.5, JH3 |
Clones, N (∼350 bp per clone) | 8 | 5 | 6 | 7 | 10 | 4 |
Mutations, N | 13 | 13 | 15 | 8 | 30 | 11 |
Mutation frequency (×10−3) | 4.6 | 8 | 7 | 3.5 | 8.7 | 8 |
. | Tumor identification no. . | |||||
---|---|---|---|---|---|---|
12437 . | 16508 . | 25787 . | 39317 . | 178119 . | 180764 . | |
VDJ | J558.74.176, DFL16.1, JH4 | J558.54.148, DST4.2, JH4 | Vh10.2b, DSP2.2, JH1 | J558.66.165, DSP2.12, JH2 | J606.1.79, DFL16.1, JH3 | J558.16.106, DSP2.5, JH3 |
Clones, N (∼350 bp per clone) | 8 | 5 | 6 | 7 | 10 | 4 |
Mutations, N | 13 | 13 | 15 | 8 | 30 | 11 |
Mutation frequency (×10−3) | 4.6 | 8 | 7 | 3.5 | 8.7 | 8 |
Each tumor was derived from a different mouse.