Table 2

Weighted Cox regression model for time to transformation

UnivariateMultivariate
HR95% CIPHR95% CIP
Grade 3A 5.3 2.4-11.8 <.001 2.5 0.7-8.3 .14 
BCL2 translocation 0.4 0.1-1.1 .07 1.0 0.3-4.1 .96 
BCL6 translocation 2.6 1.0-6.4 .05 1.5 0.3-6.3 .60 
CD10 IHC 0.2 0.1-0.6 .004 1.0 0.2-4.5 1.00 
IRF4 IHC 11.5 3.1-42.4 <.001 13.3 3.7-48.4 <.001 
UnivariateMultivariate
HR95% CIPHR95% CIP
Grade 3A 5.3 2.4-11.8 <.001 2.5 0.7-8.3 .14 
BCL2 translocation 0.4 0.1-1.1 .07 1.0 0.3-4.1 .96 
BCL6 translocation 2.6 1.0-6.4 .05 1.5 0.3-6.3 .60 
CD10 IHC 0.2 0.1-0.6 .004 1.0 0.2-4.5 1.00 
IRF4 IHC 11.5 3.1-42.4 <.001 13.3 3.7-48.4 <.001 

CI, confidence interval; HR, hazard ratio.

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