Table 3

Best ORR and durable response rates per Independent Radiology Review Committee assessment (response-evaluable population)

Response rate% (90% CI)Odds ratio* (95% CI)P†
VR-CAP, n = 76R-CHOP, n = 74
CR 64.5 (55.4-73.5) 66.2 (57.1-75.3) 0.91 (0.46-1.81) .80 
PR 28.9 32.4 – – 
ORR (CR + PR) 93.4 (88.7-98.1) 98.6 (96.4-100.0) 0.21 (0.03-1.76) .11 
Durable CR‡ 61.8 (52.6-71.0) 56.8 (47.3-66.3) 1.25 (0.64-2.42) .52 
Durable CR/PR‡ 75.0 (66.8-83.2) 78.4 (70.5-86.3) 0.84 (0.39-1.79) .65 
Response rate% (90% CI)Odds ratio* (95% CI)P†
VR-CAP, n = 76R-CHOP, n = 74
CR 64.5 (55.4-73.5) 66.2 (57.1-75.3) 0.91 (0.46-1.81) .80 
PR 28.9 32.4 – – 
ORR (CR + PR) 93.4 (88.7-98.1) 98.6 (96.4-100.0) 0.21 (0.03-1.76) .11 
Durable CR‡ 61.8 (52.6-71.0) 56.8 (47.3-66.3) 1.25 (0.64-2.42) .52 
Durable CR/PR‡ 75.0 (66.8-83.2) 78.4 (70.5-86.3) 0.84 (0.39-1.79) .65 
*

R-CHOP vs VR-CAP; an odds ratio of >1 is in favor of VR-CAP.

†

Generalized Cochran-Mantel-Haenszel test for general association (stratified by International Prognostic Index score).

‡

Durable response defined as CR or PR lasting ≥6 months.

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