Two long-chain ACs were identified as VTE-associated metabolites by untargeted metabolomics
| Name . | Molecular formula . | Molecular mass . | MH+ calculated . | m/z observed . | Retention time, min . | Fold change . | P value . |
|---|---|---|---|---|---|---|---|
| Palmitoleoyl carnitine | C23H43NO4 | 397.3192 | 398.3265 | 398.3340 | 39.9 | 1.7 ↓ | .003 |
| Decenoyl carnitine | C17H31NO4 | 313.2253 | 314.2326 | 314.2337 | 28.7 | 1.6 ↓ | .02 |
| Name . | Molecular formula . | Molecular mass . | MH+ calculated . | m/z observed . | Retention time, min . | Fold change . | P value . |
|---|---|---|---|---|---|---|---|
| Palmitoleoyl carnitine | C23H43NO4 | 397.3192 | 398.3265 | 398.3340 | 39.9 | 1.7 ↓ | .003 |
| Decenoyl carnitine | C17H31NO4 | 313.2253 | 314.2326 | 314.2337 | 28.7 | 1.6 ↓ | .02 |
Among 9400 features, the untargeted metabolomics identified 2 metabolites from the long-chain AC’s family, based on mass accuracy and retention time, which had significantly different levels between VTE and controls. The fold change reflects the average decrease in VTE subjects compared with controls. The observed and calculated m/z are given. P values were obtained using student t test.