Differences by treatment group in markers of inflammation, hemolysis, and endothelial activation from ED to 25 hours of treatment
| Biomarker . | Magnesium (n = 77) . | Placebo (n = 85) . | P* . |
|---|---|---|---|
| Interferon γ, median (IQR) | 8.39 (−59.03 to 64.10) | −13.80 (−71.82 to 40.52) | .36 |
| Interleukin 1β, median (IQR) | 0.02 (−1.00 to 0.65) | −0.14 (−0.80 to 0.50) | .43 |
| Interleukin 6, median (IQR) | 2.36 (−5.05 to 11.53) | −0.65 (−9.65 to 4.72) | .25 |
| Nitrite, median (IQR) | 0.01 (−0.03 to 0.05) | 0.01 (−0.03 to 0.05) | .99 |
| Tumor necrosis factor α, median (IQR) | −0.80 (−6.93 to 2.66) | −0.28 (−4.97 to 3.17) | .94 |
| sP_selectin, median (IQR) | 1.84 (−7.31 to 11.91) | −2.65 (−11.67 to 6.00) | .07 |
| sVascular cell adhesion molecule 1, median (IQR) | 90.48 (−4.54 to 238.98) | 86.76 (−1.16 to 198.41) | .20 |
| Biomarker . | Magnesium (n = 77) . | Placebo (n = 85) . | P* . |
|---|---|---|---|
| Interferon γ, median (IQR) | 8.39 (−59.03 to 64.10) | −13.80 (−71.82 to 40.52) | .36 |
| Interleukin 1β, median (IQR) | 0.02 (−1.00 to 0.65) | −0.14 (−0.80 to 0.50) | .43 |
| Interleukin 6, median (IQR) | 2.36 (−5.05 to 11.53) | −0.65 (−9.65 to 4.72) | .25 |
| Nitrite, median (IQR) | 0.01 (−0.03 to 0.05) | 0.01 (−0.03 to 0.05) | .99 |
| Tumor necrosis factor α, median (IQR) | −0.80 (−6.93 to 2.66) | −0.28 (−4.97 to 3.17) | .94 |
| sP_selectin, median (IQR) | 1.84 (−7.31 to 11.91) | −2.65 (−11.67 to 6.00) | .07 |
| sVascular cell adhesion molecule 1, median (IQR) | 90.48 (−4.54 to 238.98) | 86.76 (−1.16 to 198.41) | .20 |
Analyzed using a Van Elteren test.