Table 1

Demographic characteristics of hospitalizations in platelet consumptive disorders: TTP, HIT, and ITP using the NIS dataset between 2007 and 2011

ParametersTTPHITITP
Total hospitalizations, N (2007-2011) 10 624 6332 79 980 
Number of hospital admissions per year    
 2007 1801 * 16 442 
 2008 2061 362 15 123 
 2009 2266 2159 15 653 
 2010 2306 1956 17 057 
 2011 2191 1855 15 704 
Age    
 Mean age ± SD (y) 47.8 ± 0.5 61.6 ± 0.5 45.5 ± 0.7 
 Median age (y) 47.4 61.8 47.5 
 Age distribution (%)    
  Pediatric (<18 y) 1.9 0.5 20.9 
  Adult (≥18 y) 98.1 99.5 79.1 
Gender    
 Female (%) 66.6 48.7 43.4 
Race/ethnicity (%)    
 White 52.4 70.2 63.4 
 Black 33.0 13.5 12.9 
 Hispanic 8.8 9.0 15.8 
 Asian or Pacific Islander 2.6 3.0 3.1 
 Other 3.3 4.3 4.8 
Transfusion practices during hospitalization    
 Admissions with platelet transfusions (%) 10.1 7.1 25.8 
  <18 y 19.4 7.7 4.6 
  ≥18 y 10.0 6.3 31.4 
 Admissions with RBC transfusions (%) 36.4 16.7 11.9 
  <18 y 39.4  3.4 
  ≥18 y 36.4 16.7 14.1 
Most common associated procedures (%)    
 Plasma exchange/plasma infusion (75.3) RBC transfusion (16.6) IVIG administration (20.9) 
 Hemodialysis (26.9) Hemodialysis (12.4) Splenectomy (11.9) 
 Mechanical ventilation (12.5) Plasma infusion (4.7) Simple plasma infusion (3.0) 
ParametersTTPHITITP
Total hospitalizations, N (2007-2011) 10 624 6332 79 980 
Number of hospital admissions per year    
 2007 1801 * 16 442 
 2008 2061 362 15 123 
 2009 2266 2159 15 653 
 2010 2306 1956 17 057 
 2011 2191 1855 15 704 
Age    
 Mean age ± SD (y) 47.8 ± 0.5 61.6 ± 0.5 45.5 ± 0.7 
 Median age (y) 47.4 61.8 47.5 
 Age distribution (%)    
  Pediatric (<18 y) 1.9 0.5 20.9 
  Adult (≥18 y) 98.1 99.5 79.1 
Gender    
 Female (%) 66.6 48.7 43.4 
Race/ethnicity (%)    
 White 52.4 70.2 63.4 
 Black 33.0 13.5 12.9 
 Hispanic 8.8 9.0 15.8 
 Asian or Pacific Islander 2.6 3.0 3.1 
 Other 3.3 4.3 4.8 
Transfusion practices during hospitalization    
 Admissions with platelet transfusions (%) 10.1 7.1 25.8 
  <18 y 19.4 7.7 4.6 
  ≥18 y 10.0 6.3 31.4 
 Admissions with RBC transfusions (%) 36.4 16.7 11.9 
  <18 y 39.4  3.4 
  ≥18 y 36.4 16.7 14.1 
Most common associated procedures (%)    
 Plasma exchange/plasma infusion (75.3) RBC transfusion (16.6) IVIG administration (20.9) 
 Hemodialysis (26.9) Hemodialysis (12.4) Splenectomy (11.9) 
 Mechanical ventilation (12.5) Plasma infusion (4.7) Simple plasma infusion (3.0) 
*

No independent ICD-9 code for HIT prior to 2008.

Number <10 (too few to report per HCUP criteria).

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