Table 2

Clinical characteristics of patients by B2M immunohistochemistry

Total cohortΒ2M positiveΒ2M negativeP
Median age (range), y 32 (11-85) 47 (11-85) 30 (13-76) <.0001* 
Males, n (%) 80/145 (55) 35/52 (67) 45/93 (48) .037* 
Histology     
 NS, n (%) 105/145 (72) 25/52 (48) 80/93 (86) <.0001* 
 MC, n (%) 30/145 (21) 23/52 (44) 7/93 (8) <.0001* 
 Other or     
  intermediate, n (%) 9/145 (6) 3/52 (6) 6/93 (6) 
Stage     
 I/II, n (%) 84/129 (66) 20/45 (44) 63/85 (74) .0011* 
 III/IV, n (%) 47/129 (36) 25/45 (56) 22/85 (26) .0011* 
B symptoms, n (%) 47/113 (41) 19/39 (49) 28/74 (38) .32 
Bulk disease, n (%) 17/127 (13) 2/47 (4) 15/80 (19) .029 
Total cohortΒ2M positiveΒ2M negativeP
Median age (range), y 32 (11-85) 47 (11-85) 30 (13-76) <.0001* 
Males, n (%) 80/145 (55) 35/52 (67) 45/93 (48) .037* 
Histology     
 NS, n (%) 105/145 (72) 25/52 (48) 80/93 (86) <.0001* 
 MC, n (%) 30/145 (21) 23/52 (44) 7/93 (8) <.0001* 
 Other or     
  intermediate, n (%) 9/145 (6) 3/52 (6) 6/93 (6) 
Stage     
 I/II, n (%) 84/129 (66) 20/45 (44) 63/85 (74) .0011* 
 III/IV, n (%) 47/129 (36) 25/45 (56) 22/85 (26) .0011* 
B symptoms, n (%) 47/113 (41) 19/39 (49) 28/74 (38) .32 
Bulk disease, n (%) 17/127 (13) 2/47 (4) 15/80 (19) .029 

The total cohort included 145 patients; 52 B2M positive and 93 B2M negative.

*

Statistically significant difference according to a P value of <.05.

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