Basic patient characteristics of the 10 t(1;19)-positive samples injected into NSG mice
Patient . | Mer group . | Age, y . | Sex, M/F . | Patient CNS status . | Mer/697 FACS . | Xenograft CNS . |
---|---|---|---|---|---|---|
1 | High | 4.0 | M | 2b | 0.97 | + |
2 | High | 17.6 | M | 3c | 0.70 | ++ |
3 | High | 8.3 | F | 2b | 1.32 | ++ |
4 | High | 10.3 | M | 2c | 0.79 | ++ |
5 | High | 3.7 | M | 3b | 0.97 | ++ |
6 | High | 11.3 | M | 3c | 0.70 | + |
7 | Low | 11.1 | M | 1 | 0 | − |
8 | Low | 12.4 | F | 3c | 0 | − |
9 | Low | 14.5 | F | 1 | 0.25 | + |
10 | Low | 12.8 | F | 1 | 0.18 | + |
Patient . | Mer group . | Age, y . | Sex, M/F . | Patient CNS status . | Mer/697 FACS . | Xenograft CNS . |
---|---|---|---|---|---|---|
1 | High | 4.0 | M | 2b | 0.97 | + |
2 | High | 17.6 | M | 3c | 0.70 | ++ |
3 | High | 8.3 | F | 2b | 1.32 | ++ |
4 | High | 10.3 | M | 2c | 0.79 | ++ |
5 | High | 3.7 | M | 3b | 0.97 | ++ |
6 | High | 11.3 | M | 3c | 0.70 | + |
7 | Low | 11.1 | M | 1 | 0 | − |
8 | Low | 12.4 | F | 3c | 0 | − |
9 | Low | 14.5 | F | 1 | 0.25 | + |
10 | Low | 12.8 | F | 1 | 0.18 | + |
Mer expression levels are expressed in reference to the 697 cell line. The CNS status of the patient and the xenografted animals according to the semiquantitative scoring are provided. Definitions of patient CNS status are provided in Table 2.