Expression of procaspase mRNAs in CLL lymphocytes
| Function3 . | Gene name . | Protein name . | Positive samples/ Total samples . |
|---|---|---|---|
| Apoptosis initiator | CASP2 | Caspase-2 | 12/12 |
| Apoptosis initiator | CASP8 | Caspase-8 | 12/12 |
| Apoptosis initiator | CASP9 | Caspase-9 | 12/12 |
| Apoptosis initiator | CASP10 | Caspase-10 | 12/12 |
| Apoptosis effector | CASP3 | Caspase-3 | 12/12 |
| Apoptosis effector | CASP7 | Caspase-7 | 12/12 |
| Apoptosis effector | CASP6 | Caspase-6 | 12/12 |
| Proinflammatory and pyroptotic | CASP1 | Caspase-1 | 12/12 |
| Proinflammatory and pyroptotic | CASP4 | Caspase-4 | 12/12 |
| Proinflammatory and pyroptotic | CASP5 | Caspase-5 | 4/12 |
| Keratinocyte differentiation | CASP14 | Caspase-14 | 0/12 |
| Function3 . | Gene name . | Protein name . | Positive samples/ Total samples . |
|---|---|---|---|
| Apoptosis initiator | CASP2 | Caspase-2 | 12/12 |
| Apoptosis initiator | CASP8 | Caspase-8 | 12/12 |
| Apoptosis initiator | CASP9 | Caspase-9 | 12/12 |
| Apoptosis initiator | CASP10 | Caspase-10 | 12/12 |
| Apoptosis effector | CASP3 | Caspase-3 | 12/12 |
| Apoptosis effector | CASP7 | Caspase-7 | 12/12 |
| Apoptosis effector | CASP6 | Caspase-6 | 12/12 |
| Proinflammatory and pyroptotic | CASP1 | Caspase-1 | 12/12 |
| Proinflammatory and pyroptotic | CASP4 | Caspase-4 | 12/12 |
| Proinflammatory and pyroptotic | CASP5 | Caspase-5 | 4/12 |
| Keratinocyte differentiation | CASP14 | Caspase-14 | 0/12 |
Comprehensive analyses of procaspase mRNAs using a real time reverse transcription–polymerase chain reaction (RT-PCR) array (microfluidic card; Applied Biosystems) were carried out in leukemic lymphocytes from 12 CLL patients.