Table 3

AEs occurred during treatment with SRL and PDN

Patient #AEs
Hypertension (grade 2) 
Worsened (preexisting) hyper-triglyceridemia (grade 3) and cushingoid changes (grade 1) 
Cushingoid changes (grade 1) 
Worsened (preexisting) type 2 diabetes (grade 2), left leg panniculitis (grade 3), and acute coronary syndrome (grade 4) requiring percutaneous angioplasty 
Worsened (preexisting) type 2 diabetes (grade 2), bilateral leg edema (grade 2), and cushingoid changes (grade 2) 
Cushingoid changes (grade 1) 
Hyper-cholesterolemia (grade 1) and hyper-triglyceridemia (grade 2) 
Hyper-triglyceridemia (grade 2), cataract (grade 2), and abdominal aorta thrombosis (grade 3) 
Interstitial pneumonitis (grade 2) 
10 Hyper-cholesterolemia (grade 1) and hyper-triglyceridemia (grade 2) 
Patient #AEs
Hypertension (grade 2) 
Worsened (preexisting) hyper-triglyceridemia (grade 3) and cushingoid changes (grade 1) 
Cushingoid changes (grade 1) 
Worsened (preexisting) type 2 diabetes (grade 2), left leg panniculitis (grade 3), and acute coronary syndrome (grade 4) requiring percutaneous angioplasty 
Worsened (preexisting) type 2 diabetes (grade 2), bilateral leg edema (grade 2), and cushingoid changes (grade 2) 
Cushingoid changes (grade 1) 
Hyper-cholesterolemia (grade 1) and hyper-triglyceridemia (grade 2) 
Hyper-triglyceridemia (grade 2), cataract (grade 2), and abdominal aorta thrombosis (grade 3) 
Interstitial pneumonitis (grade 2) 
10 Hyper-cholesterolemia (grade 1) and hyper-triglyceridemia (grade 2) 

AEs were categorized according to the National Cancer Institute’s Common Terminology Criteria for Adverse Events, version 4.24 

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