Summary of study-drug–related AEs (all grades, NCI CTC) that occurred in more than 5% of cases, according to system organ class (n = 50)
| Study-drug–related AEs . | n (%) . |
|---|---|
| Blood and lymphatic system disorders | 36 (72) |
| Anemia | 15 (30) |
| Neutropenia | 31 (62) |
| Febrile neutropenia | 4 (8) |
| Thrombocytopenia | 82 (16) |
| General disorders and administration-site conditions | 21 (42) |
| Asthenia | 7 (14) |
| Musculoskeletal and connective tissue disorders | 6 (12) |
| Cramps | 6 (12) |
| Gastrointestinal disease | 12 (24) |
| Constipation | 4 (8) |
| Diarrhea | 3 (6) |
| Nausea | 3 (6) |
| Infections | 16 (32) |
| Pneumonia/bronchitis | 9 (18) |
| Study-drug–related AEs . | n (%) . |
|---|---|
| Blood and lymphatic system disorders | 36 (72) |
| Anemia | 15 (30) |
| Neutropenia | 31 (62) |
| Febrile neutropenia | 4 (8) |
| Thrombocytopenia | 82 (16) |
| General disorders and administration-site conditions | 21 (42) |
| Asthenia | 7 (14) |
| Musculoskeletal and connective tissue disorders | 6 (12) |
| Cramps | 6 (12) |
| Gastrointestinal disease | 12 (24) |
| Constipation | 4 (8) |
| Diarrhea | 3 (6) |
| Nausea | 3 (6) |
| Infections | 16 (32) |
| Pneumonia/bronchitis | 9 (18) |