Table 4

Predictors of remission and survival: multivariate analysis

Baseline variablePRCROS
FVIII activity <1 IU/dL 0.52 (0.33-0.81)** 0.49 (0.29-0.85)* 2.40 (1.10-5.22)* 
Inhibitor concentration >20 BU/mL 0.77 (0.49-1.21) 0.75 (0.43-1.29) 1.20 (0.54-2.67) 
Female gender 1.22 (0.77-1.91) 1.30 (0.76-2.24) 0.58 (0.26-1.31) 
Age >74 y 0.94 (0.58-1.50) 0.76 (0.43-1.32) 1.76 (0.82-3.78) 
Underlying disorder    
 Autoimmunity 1.32 (0.77-2.28) 0.88 (0.45-1.72) 1.02 (0.36-2.84) 
 Malignancy 0.58 (0.28-1.21) 0.62 (0.27-1.44) 2.91 (1.12-7.52)* 
 Pregnancy 0.61 (0.23-1.65) 0.74 (0.27-2.04) — 
 WHO-PS >2 0.76 (0.48-1.21) 0.39 (0.21-0.72)** 3.38 (1.55-7.37)** 
Baseline variablePRCROS
FVIII activity <1 IU/dL 0.52 (0.33-0.81)** 0.49 (0.29-0.85)* 2.40 (1.10-5.22)* 
Inhibitor concentration >20 BU/mL 0.77 (0.49-1.21) 0.75 (0.43-1.29) 1.20 (0.54-2.67) 
Female gender 1.22 (0.77-1.91) 1.30 (0.76-2.24) 0.58 (0.26-1.31) 
Age >74 y 0.94 (0.58-1.50) 0.76 (0.43-1.32) 1.76 (0.82-3.78) 
Underlying disorder    
 Autoimmunity 1.32 (0.77-2.28) 0.88 (0.45-1.72) 1.02 (0.36-2.84) 
 Malignancy 0.58 (0.28-1.21) 0.62 (0.27-1.44) 2.91 (1.12-7.52)* 
 Pregnancy 0.61 (0.23-1.65) 0.74 (0.27-2.04) — 
 WHO-PS >2 0.76 (0.48-1.21) 0.39 (0.21-0.72)** 3.38 (1.55-7.37)** 

Data are presented as adjusted HR (CI).

*

P < .05.

**

P < .01.

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