Grade 3 or higher treatment-related toxicities occurring in 5% or more of patients
| Toxicity type . | Treatment arm . | |||
|---|---|---|---|---|
| MPT-T (n = 148) . | mPR-R (n = 150) . | |||
| Grade 3 . | Grade 4 . | Grade 3 . | Grade 4 . | |
| Hemoglobin | 11 | 5 | 8 | 3 |
| Leukocytes | 10 | 19 | 11 | 6 |
| Lymphopenia | 8 | 13 | 8 | 2 |
| Neutrophils | 8 | 33 | 7 | 36 |
| Platelets | 1 | 17 | 6 | 7 |
| Fatigue | 16 | — | 11 | 3 |
| Constipation | 8 | — | — | — |
| Dyspnea | 12 | — | 6 | — |
| Thrombosis/thrombus/embolism | 12 | 1 | 6 | 3 |
| Toxicity type . | Treatment arm . | |||
|---|---|---|---|---|
| MPT-T (n = 148) . | mPR-R (n = 150) . | |||
| Grade 3 . | Grade 4 . | Grade 3 . | Grade 4 . | |
| Hemoglobin | 11 | 5 | 8 | 3 |
| Leukocytes | 10 | 19 | 11 | 6 |
| Lymphopenia | 8 | 13 | 8 | 2 |
| Neutrophils | 8 | 33 | 7 | 36 |
| Platelets | 1 | 17 | 6 | 7 |
| Fatigue | 16 | — | 11 | 3 |
| Constipation | 8 | — | — | — |
| Dyspnea | 12 | — | 6 | — |
| Thrombosis/thrombus/embolism | 12 | 1 | 6 | 3 |
Data are presented as number of patients.