Patient demographics
Demographic . | R−/D+ (n = 18) . | R+/D− (n = 23) . | P . |
---|---|---|---|
Diagnosis | .89 | ||
AML/MDS | 4 | 8 | |
NHL | 7 | 7 | |
HL | 4 | 4 | |
CLL | 2 | 1 | |
CML | 0 | 1 | |
ALL | 0 | 1 | |
Other | 1 | 1 | |
Graft source | .99 | ||
PBSC | 17 | 22 | |
BM | 1 | 1 | |
Conditioning | .99 | ||
FM-C | 15 | 19 | |
BEAM-C | 3 | 4 | |
Donor | .63 | ||
Sib | 15 | 17 | |
MUD | 2 | 5 | |
MMUD | 1 | 1 | |
Clinically significant GvHD | .29 | ||
No | 15 | 15 | |
Yes | 3 | 8 |
Demographic . | R−/D+ (n = 18) . | R+/D− (n = 23) . | P . |
---|---|---|---|
Diagnosis | .89 | ||
AML/MDS | 4 | 8 | |
NHL | 7 | 7 | |
HL | 4 | 4 | |
CLL | 2 | 1 | |
CML | 0 | 1 | |
ALL | 0 | 1 | |
Other | 1 | 1 | |
Graft source | .99 | ||
PBSC | 17 | 22 | |
BM | 1 | 1 | |
Conditioning | .99 | ||
FM-C | 15 | 19 | |
BEAM-C | 3 | 4 | |
Donor | .63 | ||
Sib | 15 | 17 | |
MUD | 2 | 5 | |
MMUD | 1 | 1 | |
Clinically significant GvHD | .29 | ||
No | 15 | 15 | |
Yes | 3 | 8 |
R−/D+ denotes a CMV seronegative recipient from a CMV seropositive donor; R+/D− denotes a CMV seropositive recipient from a CMV seronegative donor. Clinically significant GvHD was defined as grade 2 to 4 acute or chronic extensive. Comparisons of graft source, conditioning, and clinically significant GvHD were performed using Fisher’s exact test. Comparisons of diagnosis and donor were performed using χ-square test for trend.
ALL, acute lymphoblastic leukemia; AML, acute myeloid leukemia; BEAM-C, carmustine, etoposide, cytarabine arabinoside, melphalan, and alemtuzumab; BM, bone marrow; CLL, chronic lymphocytic leukemia; CML, chronic myeloid leukemia; FM-C, fludarabine, melphalan, and alemtuzumab; HL, Hodgkin lymphoma; MDS, myelodysplasia; MMUD, mismatched unrelated donor; MUD, matched unrelated donor; NHL, non-Hodgkin lymphoma; Other, 1 patient with dendritic cell sarcoma and 1 patient with chronic granulomatous disease; PBSC, peripheral blood stem cells; Sib, sibling donor.