Somatic mutations in the LGL clone of patient 2
| Gene . | Chromosome . | Position . | Ref. base . | Var. base . | Amino acid change . | Allele frequency (%) . | Sift/PolyPhen prediction . | Somatic P value* . |
|---|---|---|---|---|---|---|---|---|
| LY9 | 1 | 160788035 | T | C | I457T | 17.27 | Tolerated/benign | 8.97 × 10−6 |
| RB1CC1 | 8 | 53570332 | G | C | P686R | 10.29 | Tolerated/benign | .00097 |
| FOXP4 | 6 | 41533673 | G | A | A59T | 14.04 | Tolerated/benign | .003229 |
| ICOSLG | 21 | 45649510 | A | G | L442P | 14.04 | Tolerated/benign | .005479 |
| Gene . | Chromosome . | Position . | Ref. base . | Var. base . | Amino acid change . | Allele frequency (%) . | Sift/PolyPhen prediction . | Somatic P value* . |
|---|---|---|---|---|---|---|---|---|
| LY9 | 1 | 160788035 | T | C | I457T | 17.27 | Tolerated/benign | 8.97 × 10−6 |
| RB1CC1 | 8 | 53570332 | G | C | P686R | 10.29 | Tolerated/benign | .00097 |
| FOXP4 | 6 | 41533673 | G | A | A59T | 14.04 | Tolerated/benign | .003229 |
| ICOSLG | 21 | 45649510 | A | G | L442P | 14.04 | Tolerated/benign | .005479 |
PolyPhen, polymorphism phenotyping; Ref, reference; Var, variant.
Somatic P value for somatic/loss of heterozygosity events.