Table 1 Patient characteristics for all... | American Society of Hematology

Table 1

Patient characteristics for all ASCT0431 patients and patients included in the pre-HCT NGS-MRD statistical analysis

	All patients		Tagging sequence determined by IgH-V(D)J in pre-HCT blast sample
	N	Percentage	N	Percentage
Total	143	100	41	100
Age
1-9	76	53	23	56
10+	67	47	18	44
Sex
Female	59	41	19	46
Male	84	59	22	54
Relapse risk group assessment
High-risk CR1	49	34	17	41
High-risk CR2	69	48	14	34
Intermediate-risk CR2	25	17	10	24
Stem cell source/HLA matching
Matched sibling	78	55	24	59
Other related donor	4	3	2	5
Unrelated donor, BM or PBSC	34	24	9	22
Unrelated donor, cord blood	27	19	6	15
Relapse risk group/stem cell source
High-risk CR1 sib	29	20	11	27
High-risk CR1 noncord nonsib	17	12	5	12
High-risk CR1 cord	3	2	1	2
High-risk CR2 sib	24	17	3	7
High-risk CR2 noncord nonsib	21	15	6	15
High-risk CR2 cord	24	17	5	12
Intermediate-risk CR2 sib	25	17	10	24
Grade of acute GVHD
None	88	62	25	61
1	20	14	8	20
2	19	13	5	12
3	9	6	2	5
4	7	5	1	2
Chronic GVHD
No	107	75	29	71
Yes	36	25	12	29
MFC-MRD status pretransplant*	N = 105		N = 40
Negative	75	71	28	70
Positive	30	29	12	30

	All patients		Tagging sequence determined by IgH-V(D)J in pre-HCT blast sample
	N	Percentage	N	Percentage
Total	143	100	41	100
Age
1-9	76	53	23	56
10+	67	47	18	44
Sex
Female	59	41	19	46
Male	84	59	22	54
Relapse risk group assessment
High-risk CR1	49	34	17	41
High-risk CR2	69	48	14	34
Intermediate-risk CR2	25	17	10	24
Stem cell source/HLA matching
Matched sibling	78	55	24	59
Other related donor	4	3	2	5
Unrelated donor, BM or PBSC	34	24	9	22
Unrelated donor, cord blood	27	19	6	15
Relapse risk group/stem cell source
High-risk CR1 sib	29	20	11	27
High-risk CR1 noncord nonsib	17	12	5	12
High-risk CR1 cord	3	2	1	2
High-risk CR2 sib	24	17	3	7
High-risk CR2 noncord nonsib	21	15	6	15
High-risk CR2 cord	24	17	5	12
Intermediate-risk CR2 sib	25	17	10	24
Grade of acute GVHD
None	88	62	25	61
1	20	14	8	20
2	19	13	5	12
3	9	6	2	5
4	7	5	1	2
Chronic GVHD
No	107	75	29	71
Yes	36	25	12	29
MFC-MRD status pretransplant*	N = 105		N = 40
Negative	75	71	28	70
Positive	30	29	12	30

One patient with deep-sequence MRD did not have flow MRD.

PBSC, peripheral blood stem cells.