Table 1 Patient characteristics in... | American Society of Hematology

Table 1

Patient characteristics in groups with and without MR toxicity

Variable	Total (n = 148)		No toxicity (n = 115)		Toxicity* (n = 33)		P
Variable	No.	%	No.	%	No.	%	P
Mean age at diagnosis, y (± SD)	60 ± 13		61 ± 13		57 ± 15		.19
Male sex	69	47	56	49	13	39	.43
Diagnosis							.09
Follicular lymphoma	122	82	95	82	27	82
Mantle cell lymphoma	14	10	8	7	6	18
Marginal zone lymphoma	9	6	9	8	0
Lymphoplasmacytic lymphoma	3	2	3	3	0
Ann Arbor stage							.40
Limited (I-II)	21	14	15	13	6	18
Advanced (III-IV)	127	86	100	87	27	82
B symptoms	19	13	17	15	2	6	.25
Extranodal involvement	96	65	73	63	23	70	.54
Transformed	21	14	17	15	4	12	1.00
Induction regimen							.046
R-CHOP/R-CVP	83	56	70	61	13	39
BR	65	44	45	39	20	61
No. of induction cycles							.13
4	6	4	3	3	3	9
5	7	5	5	4	2	6
6	135	91	107	93	28	85
Response to induction							.21
Complete response	102	69	76	67	26	79
Partial response/stable disease	45	31	38	33	7	21
Maintenance schedule							.002
Every 2 mo	41	28	24	21	17	52
Every 3 mo	107	72	91	79	16	49

Variable	Total (n = 148)		No toxicity (n = 115)		Toxicity* (n = 33)		P
Variable	No.	%	No.	%	No.	%	P
Mean age at diagnosis, y (± SD)	60 ± 13		61 ± 13		57 ± 15		.19
Male sex	69	47	56	49	13	39	.43
Diagnosis							.09
Follicular lymphoma	122	82	95	82	27	82
Mantle cell lymphoma	14	10	8	7	6	18
Marginal zone lymphoma	9	6	9	8	0
Lymphoplasmacytic lymphoma	3	2	3	3	0
Ann Arbor stage							.40
Limited (I-II)	21	14	15	13	6	18
Advanced (III-IV)	127	86	100	87	27	82
B symptoms	19	13	17	15	2	6	.25
Extranodal involvement	96	65	73	63	23	70	.54
Transformed	21	14	17	15	4	12	1.00
Induction regimen							.046
R-CHOP/R-CVP	83	56	70	61	13	39
BR	65	44	45	39	20	61
No. of induction cycles							.13
4	6	4	3	3	3	9
5	7	5	5	4	2	6
6	135	91	107	93	28	85
Response to induction							.21
Complete response	102	69	76	67	26	79
Partial response/stable disease	45	31	38	33	7	21
Maintenance schedule							.002
Every 2 mo	41	28	24	21	17	52
Every 3 mo	107	72	91	79	16	49

Proportions were compared by using the χ² method (and Fisher’s exact test) and continuous variables were compared by using the Student t test.

SD, standard deviation.

Any grade toxicity (see supplemental Table 1).