Characteristics of studies comparing pregnancy outcome in women with HbSC against women with no SCD
| . | Country . | GNI $ (year) . | Duration of study . | HbSC women, N (N pregnancies) . | No SCD, N (N pregnancies) . | Transfusion details . | Quality of reporting (NOS) of 9 . |
|---|---|---|---|---|---|---|---|
| Total N | 279 (331) | 1074 (1231) | |||||
| First author and year of publication | |||||||
| Howard 199517 | United Kingdom | 37 340 (2012) | 1991-1993 | 33 (33) | 100 (100) | 21.2% HbSC transfused in 1st or 2nd trimester (prophylactic); | 4 |
| Ngo 201018 | France | 36 720 (2012) | 1994-2004 | 33 (33) | 128 (128) | Prophylactic transfusion for all HbSC | 7 |
| Serjeant 2005*6 | Jamaica | 5120 (2012) | 1973-2004 | 43 (95) | 68 (157) | 11.6% HbSC (on clinical indications) | 6 |
| Sun 200120 | United States | 52 610 (2012) | 1980-1995 | 58 (58) | 61 (129) | 21% of HbSC (on clinical indications) vs 0% controls | 6 |
| Wilson 201223 | Ghana | 1910 (2012) | 2007-2008 | 112 (112) | 717 (717) | No data on transfusion for study population | 5 |
| . | Country . | GNI $ (year) . | Duration of study . | HbSC women, N (N pregnancies) . | No SCD, N (N pregnancies) . | Transfusion details . | Quality of reporting (NOS) of 9 . |
|---|---|---|---|---|---|---|---|
| Total N | 279 (331) | 1074 (1231) | |||||
| First author and year of publication | |||||||
| Howard 199517 | United Kingdom | 37 340 (2012) | 1991-1993 | 33 (33) | 100 (100) | 21.2% HbSC transfused in 1st or 2nd trimester (prophylactic); | 4 |
| Ngo 201018 | France | 36 720 (2012) | 1994-2004 | 33 (33) | 128 (128) | Prophylactic transfusion for all HbSC | 7 |
| Serjeant 2005*6 | Jamaica | 5120 (2012) | 1973-2004 | 43 (95) | 68 (157) | 11.6% HbSC (on clinical indications) | 6 |
| Sun 200120 | United States | 52 610 (2012) | 1980-1995 | 58 (58) | 61 (129) | 21% of HbSC (on clinical indications) vs 0% controls | 6 |
| Wilson 201223 | Ghana | 1910 (2012) | 2007-2008 | 112 (112) | 717 (717) | No data on transfusion for study population | 5 |
All studies were historical cohort studies of pregnancy except for those marked *, which were prospective pregnancy cohort studies.