Table 1

Search strategy for databases

No.Maternity and Infant Care, Medline, and Embase search strategy
exp Hemoglobin, Sickle/ or sickle.mp. or exp Anemia, Sickle Cell/ 
hemoglobinopathy.mp. or exp Hemoglobinopathies/ 
Hemoglobinopathies/ or Hemoglobins, Abnormal/ or haemoglobinopathy.mp. 
exp Pregnancy Complications/ or exp Pregnancy Trimesters/ or pregnancy.mp. or exp Pregnancy Complications, Cardiovascular/ or exp Pregnancy Complications, Infectious/ or exp Pregnancy, High-Risk/ or exp Pregnancy Complications, Hematologic/ or exp Pregnancy/ or exp Hypertension, Pregnancy-Induced/ or exp Pregnancy Trimester, Second/ or exp Pregnancy Outcome/ or exp Pregnancy Trimester, First/ or exp Pregnancy Trimester, Third/ 
1 or 2 or 3 
(pregnancy adj3 outcome).mp. [mp=title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept, rare disease supplementary concept, unique identifier] 
exp Maternal Mortality/ or maternal.mp. or exp Maternal Death/ 
exp Obstetrics/ or exp Prenatal Care/ or maternity.mp. 
pregnant.mp. or exp Placenta/ or exp Infant, Newborn/ or exp Pregnancy Complications/ or exp Fetus/ or exp Pregnancy Complications, Infectious/ or exp Pregnancy/ or exp Pregnant Women/ 
10 exp Fetal Diseases/ or antenatal.mp. 
11 exp Fetal Growth Retardation/ or fetal.mp. or exp Fetal Development/ or exp Fetal Death/ or exp Fetal Weight/ or exp Fetal Diseases/ or exp Fetal Mortality/ 
12 foetus.mp. or Fetus/ 
13 gestation.mp. or Pregnancy/ 
14 4 or 6 or 7 or 8 or 9 or 10 or 11 or 12 or 13 
15 5 and 14 
 Web of Science and Cochrane search strategy 
Sickle or sickle cell 
Hemoglobinopathy or haemoglobinopathy 
Hemoglobinopathies or haemoglobinopathies 
1 or 2 or 3 
Pregnancy or pregnant 
Maternal or maternity 
Obstetrics 
Antenatal 
Fetal or foetal 
10 Fetus or foetus 
11 Gestation 
12 5 or 6 or 7 or 8 or 9 or 10 or 11 
 Popline search strategy 
Sickle or sickle cell 
Hemoglobinopathy or haemoglobinopathy or hemoglobinopathies or haemoglobinopathies 
1 or 2 
Pregnancy or pregnant or maternal or maternity or obstetrics or antenatal or fetal or foetal or fetus or foetus or gestation 
3 and 4 
No.Maternity and Infant Care, Medline, and Embase search strategy
exp Hemoglobin, Sickle/ or sickle.mp. or exp Anemia, Sickle Cell/ 
hemoglobinopathy.mp. or exp Hemoglobinopathies/ 
Hemoglobinopathies/ or Hemoglobins, Abnormal/ or haemoglobinopathy.mp. 
exp Pregnancy Complications/ or exp Pregnancy Trimesters/ or pregnancy.mp. or exp Pregnancy Complications, Cardiovascular/ or exp Pregnancy Complications, Infectious/ or exp Pregnancy, High-Risk/ or exp Pregnancy Complications, Hematologic/ or exp Pregnancy/ or exp Hypertension, Pregnancy-Induced/ or exp Pregnancy Trimester, Second/ or exp Pregnancy Outcome/ or exp Pregnancy Trimester, First/ or exp Pregnancy Trimester, Third/ 
1 or 2 or 3 
(pregnancy adj3 outcome).mp. [mp=title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept, rare disease supplementary concept, unique identifier] 
exp Maternal Mortality/ or maternal.mp. or exp Maternal Death/ 
exp Obstetrics/ or exp Prenatal Care/ or maternity.mp. 
pregnant.mp. or exp Placenta/ or exp Infant, Newborn/ or exp Pregnancy Complications/ or exp Fetus/ or exp Pregnancy Complications, Infectious/ or exp Pregnancy/ or exp Pregnant Women/ 
10 exp Fetal Diseases/ or antenatal.mp. 
11 exp Fetal Growth Retardation/ or fetal.mp. or exp Fetal Development/ or exp Fetal Death/ or exp Fetal Weight/ or exp Fetal Diseases/ or exp Fetal Mortality/ 
12 foetus.mp. or Fetus/ 
13 gestation.mp. or Pregnancy/ 
14 4 or 6 or 7 or 8 or 9 or 10 or 11 or 12 or 13 
15 5 and 14 
 Web of Science and Cochrane search strategy 
Sickle or sickle cell 
Hemoglobinopathy or haemoglobinopathy 
Hemoglobinopathies or haemoglobinopathies 
1 or 2 or 3 
Pregnancy or pregnant 
Maternal or maternity 
Obstetrics 
Antenatal 
Fetal or foetal 
10 Fetus or foetus 
11 Gestation 
12 5 or 6 or 7 or 8 or 9 or 10 or 11 
 Popline search strategy 
Sickle or sickle cell 
Hemoglobinopathy or haemoglobinopathy or hemoglobinopathies or haemoglobinopathies 
1 or 2 
Pregnancy or pregnant or maternal or maternity or obstetrics or antenatal or fetal or foetal or fetus or foetus or gestation 
3 and 4 
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