Table 1

Symptoms of leukostasis

OrganSymptoms
Lung Dyspnea, hypoxemia, diffuse alveolar hemorrhage, respiratory failure 
Central nervous system Confusion, somnolence, dizziness, headache, delirium, coma, focal neurologic deficits 
Eye Impaired vision, retinal hemorrhage 
Ear Tinnitus 
Heart Myocardial ischemia/infarction 
Vascular system Limb ischemia, renal vein thrombosis, priapism 
OrganSymptoms
Lung Dyspnea, hypoxemia, diffuse alveolar hemorrhage, respiratory failure 
Central nervous system Confusion, somnolence, dizziness, headache, delirium, coma, focal neurologic deficits 
Eye Impaired vision, retinal hemorrhage 
Ear Tinnitus 
Heart Myocardial ischemia/infarction 
Vascular system Limb ischemia, renal vein thrombosis, priapism 

For patients presenting with 1 or more of these symptoms not attributable to preexisting or coexisting medical conditions, leukostasis is highly probable.39,40,60 

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