Characteristics of the participants included in the discovery in the Rotterdam Study I (RS-I) and in the replication in the Rotterdam Study II (RS-II)
| . | RS-I . | RS-II . |
|---|---|---|
| Sample size | 3423 | 2025 |
| Age (y) | 72.4 ± 7.0 | 64.6 ± 7.9 |
| Sex (% males) | 41.3 | 45.1 |
| ADAMTS13 activity (%) | 89.5 ± 17.4 | 95.0 ± 17.6 |
| BMI (kg/m2) | 26.8 ± 3.9 | 27.2 ± 4.0 |
| Current smoking (%) | 15.8 | 19.5 |
| Total cholesterol (mmol/L) | 5.8 ± 1.0 | 5.8 ± 1.0 |
| HDL cholesterol (mmol/L) | 1.4 ± 0.4 | 1.4 ± 0.4 |
| Systolic blood pressure (mm Hg) | 143.3 ± 21.0 | 143.1 ± 21.3 |
| Diastolic blood pressure (mm Hg) | 75.2 ± 11.2 | 78.9 ± 10.8 |
| Prevalent type 2 diabetes (%) | 14.1 | 11.5 |
| . | RS-I . | RS-II . |
|---|---|---|
| Sample size | 3423 | 2025 |
| Age (y) | 72.4 ± 7.0 | 64.6 ± 7.9 |
| Sex (% males) | 41.3 | 45.1 |
| ADAMTS13 activity (%) | 89.5 ± 17.4 | 95.0 ± 17.6 |
| BMI (kg/m2) | 26.8 ± 3.9 | 27.2 ± 4.0 |
| Current smoking (%) | 15.8 | 19.5 |
| Total cholesterol (mmol/L) | 5.8 ± 1.0 | 5.8 ± 1.0 |
| HDL cholesterol (mmol/L) | 1.4 ± 0.4 | 1.4 ± 0.4 |
| Systolic blood pressure (mm Hg) | 143.3 ± 21.0 | 143.1 ± 21.3 |
| Diastolic blood pressure (mm Hg) | 75.2 ± 11.2 | 78.9 ± 10.8 |
| Prevalent type 2 diabetes (%) | 14.1 | 11.5 |
BMI, body mass index; HDL, high-density lipoprotein.
Continuous variables are summarized by their mean ± SD.