Adverse events
| Adverse event, n (%) . | Patients (n = 68) . | |
|---|---|---|
| Any grade AE . | Grade 3 to 4 AEs . | |
| Thrombocytopenia | 58 (85, [74.6; 92.7]) | 19 (28, [17.7; 40.1]) |
| Anemia | 56 (82, [71.2; 90.6]) | 24 (35, [24.1; 47.8]) |
| Fatigue | 53 (78, [66.2; 87.1]) | 2 (3, [0.4; 10.2]) |
| Neutropenia | 44 (65, [52.2; 75.9]) | 26 (38, [26.7; 50.8]) |
| Infections | 36 (53, [39.0; 63.8]) | 5 (7, [2.4; 16.3]) |
| Nausea | 33 (48, [37.6; 62.4]) | 4 (6, [1.6; 14.4]) |
| Elevated liver enzymes | 20 (29, [19; 41.7]) | 3 (4, [0.9; 12.3]) |
| Peripheral neuropathy | 17 (25, [15.9; 37]) | 1 (1.5, [0.04; 7.9]) |
| Peripheral edema | 15 (22, [14.1; 35.4]) | 0 (0, [0; 5.2]) |
| Elevated creatinine | 14 (21, [12.6; 31.2]) | 2 (3, [0.4; 10.2]) |
| Diarrhea | 12 (18, [8.4; 27.1]) | 0 (0, [0; 5.2]) |
| Deep vein thrombosis | 4 (6, [1.6; 14.4]) | 1 (1.5, [0.04; 7.9]) |
| Congestive heart failure | 4 (6, [1.6; 14.4]) | 3 (4, [0.9; 12.3]) |
| Atrial fibrillation | 3 (4, [0.9; 12.3]) | 1 (1.5, [0.04; 7.9]) |
| Hypertension | 2 (3, [0.4; 10.2]) | 2 (3, [0.4; 10.2]) |
| Adverse event, n (%) . | Patients (n = 68) . | |
|---|---|---|
| Any grade AE . | Grade 3 to 4 AEs . | |
| Thrombocytopenia | 58 (85, [74.6; 92.7]) | 19 (28, [17.7; 40.1]) |
| Anemia | 56 (82, [71.2; 90.6]) | 24 (35, [24.1; 47.8]) |
| Fatigue | 53 (78, [66.2; 87.1]) | 2 (3, [0.4; 10.2]) |
| Neutropenia | 44 (65, [52.2; 75.9]) | 26 (38, [26.7; 50.8]) |
| Infections | 36 (53, [39.0; 63.8]) | 5 (7, [2.4; 16.3]) |
| Nausea | 33 (48, [37.6; 62.4]) | 4 (6, [1.6; 14.4]) |
| Elevated liver enzymes | 20 (29, [19; 41.7]) | 3 (4, [0.9; 12.3]) |
| Peripheral neuropathy | 17 (25, [15.9; 37]) | 1 (1.5, [0.04; 7.9]) |
| Peripheral edema | 15 (22, [14.1; 35.4]) | 0 (0, [0; 5.2]) |
| Elevated creatinine | 14 (21, [12.6; 31.2]) | 2 (3, [0.4; 10.2]) |
| Diarrhea | 12 (18, [8.4; 27.1]) | 0 (0, [0; 5.2]) |
| Deep vein thrombosis | 4 (6, [1.6; 14.4]) | 1 (1.5, [0.04; 7.9]) |
| Congestive heart failure | 4 (6, [1.6; 14.4]) | 3 (4, [0.9; 12.3]) |
| Atrial fibrillation | 3 (4, [0.9; 12.3]) | 1 (1.5, [0.04; 7.9]) |
| Hypertension | 2 (3, [0.4; 10.2]) | 2 (3, [0.4; 10.2]) |
Data are presented as n (%, [95% CI]).