The top 10 differentially regulated genes in Tg HSCs
| Refseq_name . | Gene symbol . | Ctrl . | Tg . | Tg/Ctrl . | Description . |
|---|---|---|---|---|---|
| Genes upregulated in Tg HSCs | |||||
| NM_008741 | Nsg2 | 1.37 | 62.8 | 45.9 | Neuron-specific gene family member 2 |
| NM_013805 | Cldn5 | 0.37 | 2.49 | 6.73 | Claudin 5 |
| NM_001018013 | Izumo1 | 0.80 | 4.93 | 6.16 | Izumo sperm-egg fusion 1 |
| NM_178618 | Fam83g | 0.58 | 2.33 | 4.02 | Family with sequence similarity 83, member G |
| NM_001033227 | Slc5a10 | 1.32 | 5.10 | 3.86 | Solute carrier family 5, member 10 |
| NM_011627 | Tpbg | 0.59 | 2.19 | 3.71 | Trophoblast glycoprotein |
| NM_010738 | Ly6a | 21.9 | 78.5 | 3.58 | Lymphocyte antigen 6 complex, locus A |
| NM_010218 | Fjx1 | 0.70 | 2.38 | 3.40 | Four jointed box 1 |
| NM_001159748 | Serpinb8 | 0.90 | 3.02 | 3.36 | Serine (or cysteine) peptidase inhibitor, clade B, member 8 |
| NM_007388 | Acp5 | 0.75 | 2.41 | 3.21 | Acid phosphatase 5, tartrate resistant |
| Genes downregulated in Tg HSCs | |||||
| NM_181596 | Retnlg | 8.31 | 1.23 | 0.15 | Resistin-like γ |
| NM_008611 | Mmp8 | 1.87 | 0.28 | 0.15 | Matrix metallopeptidase 8 |
| NM_008405 | Itgb2l | 2.97 | 0.55 | 0.19 | Integrin β2-like |
| NM_145143 | Mpp4 | 2.80 | 0.66 | 0.24 | MAGUK p55 subfamily member 4 |
| NM_021407 | Trem3 | 4.36 | 1.07 | 0.25 | Triggering receptor expressed on myeloid cells 3 |
| NM_013599 | Mmp9 | 4.20 | 1.04 | 0.25 | Matrix metallopeptidase 9 |
| NM_009639 | Crisp3 | 2.51 | 0.63 | 0.25 | Cysteine-rich secretory protein 3 |
| NM_011410 | Slfn4 | 1.08 | 0.28 | 0.26 | Schlafen 4 |
| NM_145389 | BC016579 | 4.44 | 1.20 | 0.27 | cDNA sequence, BC016579 |
| NM_178885 | AI182371 | 1.36 | 0.37 | 0.27 | Expressed sequence AI182371 |
| Refseq_name . | Gene symbol . | Ctrl . | Tg . | Tg/Ctrl . | Description . |
|---|---|---|---|---|---|
| Genes upregulated in Tg HSCs | |||||
| NM_008741 | Nsg2 | 1.37 | 62.8 | 45.9 | Neuron-specific gene family member 2 |
| NM_013805 | Cldn5 | 0.37 | 2.49 | 6.73 | Claudin 5 |
| NM_001018013 | Izumo1 | 0.80 | 4.93 | 6.16 | Izumo sperm-egg fusion 1 |
| NM_178618 | Fam83g | 0.58 | 2.33 | 4.02 | Family with sequence similarity 83, member G |
| NM_001033227 | Slc5a10 | 1.32 | 5.10 | 3.86 | Solute carrier family 5, member 10 |
| NM_011627 | Tpbg | 0.59 | 2.19 | 3.71 | Trophoblast glycoprotein |
| NM_010738 | Ly6a | 21.9 | 78.5 | 3.58 | Lymphocyte antigen 6 complex, locus A |
| NM_010218 | Fjx1 | 0.70 | 2.38 | 3.40 | Four jointed box 1 |
| NM_001159748 | Serpinb8 | 0.90 | 3.02 | 3.36 | Serine (or cysteine) peptidase inhibitor, clade B, member 8 |
| NM_007388 | Acp5 | 0.75 | 2.41 | 3.21 | Acid phosphatase 5, tartrate resistant |
| Genes downregulated in Tg HSCs | |||||
| NM_181596 | Retnlg | 8.31 | 1.23 | 0.15 | Resistin-like γ |
| NM_008611 | Mmp8 | 1.87 | 0.28 | 0.15 | Matrix metallopeptidase 8 |
| NM_008405 | Itgb2l | 2.97 | 0.55 | 0.19 | Integrin β2-like |
| NM_145143 | Mpp4 | 2.80 | 0.66 | 0.24 | MAGUK p55 subfamily member 4 |
| NM_021407 | Trem3 | 4.36 | 1.07 | 0.25 | Triggering receptor expressed on myeloid cells 3 |
| NM_013599 | Mmp9 | 4.20 | 1.04 | 0.25 | Matrix metallopeptidase 9 |
| NM_009639 | Crisp3 | 2.51 | 0.63 | 0.25 | Cysteine-rich secretory protein 3 |
| NM_011410 | Slfn4 | 1.08 | 0.28 | 0.26 | Schlafen 4 |
| NM_145389 | BC016579 | 4.44 | 1.20 | 0.27 | cDNA sequence, BC016579 |
| NM_178885 | AI182371 | 1.36 | 0.37 | 0.27 | Expressed sequence AI182371 |
The values indicate reads per kilobase of transcript per million mapped reads and the Tg vs control.