Frequency of CD8+ T-cell IFN-γ immune responses against TAAs and CMV in 114 HLA-A*02:01+ volunteer blood donors (cross-sectional study group I)
. | All donors . | Nulligravidous women . | Primi-/multiparous women . | Men . | ||||
---|---|---|---|---|---|---|---|---|
n . | % . | n . | % . | n . | % . | n . | % . | |
HER2/neu | ||||||||
0.1 µmol/L | 3/112 | 3 | 0/37 | 0 | 1/38 | 3 | 2/37 | 5 |
10 µmol/L | 4/110 | 4 | 0/37 | 0 | 1/36 | 3 | 3/37 | 8 |
0.1 and/or 10 µmol/L | 6/114 | 5 | 0/38 | 0 | 2/38 | 5 | 4/38 | 11 |
MUC1 | ||||||||
0.1 µmol/L | 8/109 | 7 | 3/37 | 8 | 3/37 | 8 | 2/35 | 6 |
10 µmol/L | 9/110 | 8 | 3/37 | 8 | 3/36 | 8 | 3/37 | 8 |
0.1 and/or 10 µmol/L | 16/114 | 14 | 6/38 | 16 | 6/38 | 16 | 4/38 | 11 |
PRAME | ||||||||
0.1 µmol/L | 3/113 | 3 | 0/37 | 0 | 0/38 | 0 | 3/38 | 8 |
10 µmol/L | 7/111 | 6 | 2/37 | 5 | 0/36 | 0 | 5/38 | 13 |
0.1 and/or 10 µmol/L | 8/114 | 7 | 2/38 | 5 | 0/38 | 0 | 6/38 | 16 |
WT1 | ||||||||
0.1 µmol/L | 11/114 | 10 | 4/38 | 11 | 4/38 | 11 | 3/38 | 8 |
10 µmol/L | 9/112 | 8 | 3/38 | 8 | 2/36 | 6 | 4/38 | 11 |
0.1 and/or 10 µmol/L | 17/114 | 15 | 5/38 | 13 | 6/38 | 16 | 6/38 | 16 |
CMV | ||||||||
10 µmol/L | 42/111 | 38 | 8/37 | 22 | 20/37 | 54 | 14/37 | 38 |
. | All donors . | Nulligravidous women . | Primi-/multiparous women . | Men . | ||||
---|---|---|---|---|---|---|---|---|
n . | % . | n . | % . | n . | % . | n . | % . | |
HER2/neu | ||||||||
0.1 µmol/L | 3/112 | 3 | 0/37 | 0 | 1/38 | 3 | 2/37 | 5 |
10 µmol/L | 4/110 | 4 | 0/37 | 0 | 1/36 | 3 | 3/37 | 8 |
0.1 and/or 10 µmol/L | 6/114 | 5 | 0/38 | 0 | 2/38 | 5 | 4/38 | 11 |
MUC1 | ||||||||
0.1 µmol/L | 8/109 | 7 | 3/37 | 8 | 3/37 | 8 | 2/35 | 6 |
10 µmol/L | 9/110 | 8 | 3/37 | 8 | 3/36 | 8 | 3/37 | 8 |
0.1 and/or 10 µmol/L | 16/114 | 14 | 6/38 | 16 | 6/38 | 16 | 4/38 | 11 |
PRAME | ||||||||
0.1 µmol/L | 3/113 | 3 | 0/37 | 0 | 0/38 | 0 | 3/38 | 8 |
10 µmol/L | 7/111 | 6 | 2/37 | 5 | 0/36 | 0 | 5/38 | 13 |
0.1 and/or 10 µmol/L | 8/114 | 7 | 2/38 | 5 | 0/38 | 0 | 6/38 | 16 |
WT1 | ||||||||
0.1 µmol/L | 11/114 | 10 | 4/38 | 11 | 4/38 | 11 | 3/38 | 8 |
10 µmol/L | 9/112 | 8 | 3/38 | 8 | 2/36 | 6 | 4/38 | 11 |
0.1 and/or 10 µmol/L | 17/114 | 15 | 5/38 | 13 | 6/38 | 16 | 6/38 | 16 |
CMV | ||||||||
10 µmol/L | 42/111 | 38 | 8/37 | 22 | 20/37 | 54 | 14/37 | 38 |