Densitometry for western blots for Figure 3E
. | Mec-1 . | OSU-CLL . | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
C . | T315 . | Okadaic acid . | T315+Oka . | OSU-03012 . | OSU-03012+Oka . | C . | T315 . | Okadaic acid . | T315+Oka . | OSU-03012 . | OSU-03012+Oka . | |
P-Craf | 12.8 | 5.9 | 15.0 | 7.0 | 10.5 | 11.9 | 10.4 | 5.8 | 12.7 | 6.6 | 7.1 | 9.3 |
P-AKTSer473 | 6.0 | 3.1 | 8.9 | 3.1 | 3.9 | 6.6 | 9.7 | 3.3 | 10.0 | 3.1 | 6.8 | 8.9 |
P-FAKThr308 | 8.7 | 5.7 | 12.6 | 6.3 | 6.2 | 10.6 | 8.1 | 5.6 | 11.4 | 5.6 | 6.5 | 9.8 |
P-GSK3β | 6.1 | 4.4 | 8.3 | 6.4 | 4.8 | 7.7 | 4.1 | 2.7 | 8.4 | 5.3 | 4.1 | 7.0 |
P-ERK | 15.9 | 3.4 | 21.5 | 7.0 | 15.8 | 20.0 | 14.2 | 5.5 | 19.6 | 8.1 | 10.8 | 16.9 |
. | Mec-1 . | OSU-CLL . | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
C . | T315 . | Okadaic acid . | T315+Oka . | OSU-03012 . | OSU-03012+Oka . | C . | T315 . | Okadaic acid . | T315+Oka . | OSU-03012 . | OSU-03012+Oka . | |
P-Craf | 12.8 | 5.9 | 15.0 | 7.0 | 10.5 | 11.9 | 10.4 | 5.8 | 12.7 | 6.6 | 7.1 | 9.3 |
P-AKTSer473 | 6.0 | 3.1 | 8.9 | 3.1 | 3.9 | 6.6 | 9.7 | 3.3 | 10.0 | 3.1 | 6.8 | 8.9 |
P-FAKThr308 | 8.7 | 5.7 | 12.6 | 6.3 | 6.2 | 10.6 | 8.1 | 5.6 | 11.4 | 5.6 | 6.5 | 9.8 |
P-GSK3β | 6.1 | 4.4 | 8.3 | 6.4 | 4.8 | 7.7 | 4.1 | 2.7 | 8.4 | 5.3 | 4.1 | 7.0 |
P-ERK | 15.9 | 3.4 | 21.5 | 7.0 | 15.8 | 20.0 | 14.2 | 5.5 | 19.6 | 8.1 | 10.8 | 16.9 |