Densitometry for western blots for Figure 3A
| . | Mec-1 . | OSU-CLL . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| C . | 1 μM . | 2 μM . | 3 μM . | 4 μM . | C . | 1 μM . | 2 μM . | 3 μM . | 4 μM . | |
| P-FAKTyr397 | 6.5 | 8.2 | 6.2 | 5.1 | 5.0 | 2.2 | 1.9 | 2.4 | 2.6 | 2.4 |
| P-FAKTyr925 | 4.2 | 3.6 | 4.7 | 4.0 | 3.5 | 2.8 | 3.5 | 4.3 | 3.7 | 3.2 |
| P-BTK | 5.0 | 6.2 | 6.2 | 5.8 | 5.7 | 7.5 | 7.7 | 9.1 | 9.1 | 8.5 |
| P-AKTSer473 | 11.1 | 6.5 | 3.2 | 1.9 | 1.8 | 15.1 | 10.0 | 6.6 | 3.1 | 2.3 |
| P-FAKThr308 | 13.6 | 6.9 | 7.1 | 3.7 | 2.8 | 14.3 | 6.5 | 3.6 | 3.3 | 2.4 |
| P-Craf | 17.6 | 16.7 | 11.7 | 8.1 | 6.4 | 14.0 | 9.6 | 8.4 | 6.4 | 6.2 |
| P-ERK | 15.9 | 7.5 | 2.9 | 2.6 | 2.6 | 12.6 | 6.5 | 7.7 | 7.4 | 7.5 |
| P-P38 | 8.4 | 8.1 | 7.1 | 5.7 | 4.5 | 5.6 | 6.4 | 7.0 | 5.8 | 4.1 |
| P-GSK3β | 6.3 | 5.2 | 4.8 | 4.1 | 3.0 | 6.9 | 4.9 | 3.9 | 3.3 | 3.6 |
| P-PDK1 | 4.3 | 5.0 | 5.4 | 5.0 | 4.3 | 4.3 | 5.0 | 6.6 | 5.8 | 5.2 |
| . | Mec-1 . | OSU-CLL . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| C . | 1 μM . | 2 μM . | 3 μM . | 4 μM . | C . | 1 μM . | 2 μM . | 3 μM . | 4 μM . | |
| P-FAKTyr397 | 6.5 | 8.2 | 6.2 | 5.1 | 5.0 | 2.2 | 1.9 | 2.4 | 2.6 | 2.4 |
| P-FAKTyr925 | 4.2 | 3.6 | 4.7 | 4.0 | 3.5 | 2.8 | 3.5 | 4.3 | 3.7 | 3.2 |
| P-BTK | 5.0 | 6.2 | 6.2 | 5.8 | 5.7 | 7.5 | 7.7 | 9.1 | 9.1 | 8.5 |
| P-AKTSer473 | 11.1 | 6.5 | 3.2 | 1.9 | 1.8 | 15.1 | 10.0 | 6.6 | 3.1 | 2.3 |
| P-FAKThr308 | 13.6 | 6.9 | 7.1 | 3.7 | 2.8 | 14.3 | 6.5 | 3.6 | 3.3 | 2.4 |
| P-Craf | 17.6 | 16.7 | 11.7 | 8.1 | 6.4 | 14.0 | 9.6 | 8.4 | 6.4 | 6.2 |
| P-ERK | 15.9 | 7.5 | 2.9 | 2.6 | 2.6 | 12.6 | 6.5 | 7.7 | 7.4 | 7.5 |
| P-P38 | 8.4 | 8.1 | 7.1 | 5.7 | 4.5 | 5.6 | 6.4 | 7.0 | 5.8 | 4.1 |
| P-GSK3β | 6.3 | 5.2 | 4.8 | 4.1 | 3.0 | 6.9 | 4.9 | 3.9 | 3.3 | 3.6 |
| P-PDK1 | 4.3 | 5.0 | 5.4 | 5.0 | 4.3 | 4.3 | 5.0 | 6.6 | 5.8 | 5.2 |