Cytogenetically defined risk-based classification of SMM
| Risk . | Cytogenetic finding . |
|---|---|
| High | t(4;14) |
| del(17p) | |
| 1q gain | |
| Intermediate | Trisomies without IgH translocation |
| Standard | Other IgH translocations including t(11;14), t(14;16), and t(14;20) |
| Presence of trisomies and IgH translocation, except t(4;14) | |
| Monosomy13/del(13q) | |
| Low | No abnormalities (normal or insufficient) |
| Risk . | Cytogenetic finding . |
|---|---|
| High | t(4;14) |
| del(17p) | |
| 1q gain | |
| Intermediate | Trisomies without IgH translocation |
| Standard | Other IgH translocations including t(11;14), t(14;16), and t(14;20) |
| Presence of trisomies and IgH translocation, except t(4;14) | |
| Monosomy13/del(13q) | |
| Low | No abnormalities (normal or insufficient) |
IgH, immunoglobulin heavy chain.
Adapted from Rajkumar et al31 with permission.