Subgroup analysis with stratification by gender
| . | Men . | Women . | ||||
|---|---|---|---|---|---|---|
| . | Adjusted HR (95% CI)* . | Adjusted HR (95% CI)* . | ||||
| Outcome . | Overall . | 0-365 d of follow-up . | >365 d of follow-up . | Overall . | 0-365 d of follow-up . | >365 d of follow-up . |
| VTE | 11.28 (10.37-12.27) | 36.57 (31.23-42.81) | 7.70 (6.95-8.53) | 6.92 (6.40-7.48) | 26.16 (22.57-30.31) | 4.81 (4.37-5.28) |
| Unprovoked VTE | 13.19 (11.93-14.57) | 37.96 (31.26-46.10) | 9.60 (8.53-10.81) | 8.05 (7.33-8.84) | 26.71 (22.22-32.10) | 5.98 (5.36-6.67) |
| Provoked VTE | 7.90 (6.75-9.25) | 29.67 (22.42-39.25) | 4.64 (3.77-5.72) | 5.07 (4.38-5.87) | 22.51 (17.40-29.13) | 3.01 (2.48-3.64) |
| DVT | 14.34 (12.98-15.85) | 46.31 (38.38-55.88) | 9.55 (8.45-10.80) | 9.26 (8.41-10.19) | 37.44 (31.05-45.14) | 6.33 (5.64-7.11) |
| PE | 5.81 (4.97-6.80) | 19.63 (14.49-26.60) | 4.27 (3.54-5.14) | 3.83 (3.34-4.40) | 14.07 (10.92-18.14) | 2.73 (2.31-3.23) |
| AMI | 1.25 (1.11-1.40) | 1.51 (1.09-2.09) | 1.22 (1.07-1.38) | 1.09 (0.96-1.24) | 1.72 (1.25-2.36) | 1.02 (0.89-1.17) |
| Ischemic stroke | 1.36 (1.21-1.53) | 1.72 (1.21-2.45) | 1.32 (1.17-1.50) | 1.22 (1.10-1.35) | 1.79 (1.33-2.41) | 1.17 (1.05-1.31) |
| Death | 1.34 (1.28-1.41) | 2.82 (2.53-3.15) | 1.19 (1.13-1.25) | 1.22 (1.18-1.27) | 2.29 (2.08-2.53) | 1.12 (1.07-1.17) |
| . | Men . | Women . | ||||
|---|---|---|---|---|---|---|
| . | Adjusted HR (95% CI)* . | Adjusted HR (95% CI)* . | ||||
| Outcome . | Overall . | 0-365 d of follow-up . | >365 d of follow-up . | Overall . | 0-365 d of follow-up . | >365 d of follow-up . |
| VTE | 11.28 (10.37-12.27) | 36.57 (31.23-42.81) | 7.70 (6.95-8.53) | 6.92 (6.40-7.48) | 26.16 (22.57-30.31) | 4.81 (4.37-5.28) |
| Unprovoked VTE | 13.19 (11.93-14.57) | 37.96 (31.26-46.10) | 9.60 (8.53-10.81) | 8.05 (7.33-8.84) | 26.71 (22.22-32.10) | 5.98 (5.36-6.67) |
| Provoked VTE | 7.90 (6.75-9.25) | 29.67 (22.42-39.25) | 4.64 (3.77-5.72) | 5.07 (4.38-5.87) | 22.51 (17.40-29.13) | 3.01 (2.48-3.64) |
| DVT | 14.34 (12.98-15.85) | 46.31 (38.38-55.88) | 9.55 (8.45-10.80) | 9.26 (8.41-10.19) | 37.44 (31.05-45.14) | 6.33 (5.64-7.11) |
| PE | 5.81 (4.97-6.80) | 19.63 (14.49-26.60) | 4.27 (3.54-5.14) | 3.83 (3.34-4.40) | 14.07 (10.92-18.14) | 2.73 (2.31-3.23) |
| AMI | 1.25 (1.11-1.40) | 1.51 (1.09-2.09) | 1.22 (1.07-1.38) | 1.09 (0.96-1.24) | 1.72 (1.25-2.36) | 1.02 (0.89-1.17) |
| Ischemic stroke | 1.36 (1.21-1.53) | 1.72 (1.21-2.45) | 1.32 (1.17-1.50) | 1.22 (1.10-1.35) | 1.79 (1.33-2.41) | 1.17 (1.05-1.31) |
| Death | 1.34 (1.28-1.41) | 2.82 (2.53-3.15) | 1.19 (1.13-1.25) | 1.22 (1.18-1.27) | 2.29 (2.08-2.53) | 1.12 (1.07-1.17) |
Adjusted for cancer, pregnancy, fracture, surgery, CCI score, and autoimmune diseases.